ArticleScientific reports2023
Incidence of bacterial and fungal infections in Polish pediatric patients with acute lymphoblastic leukemia during the pandemic.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 4 citations in OpenAlex.
- Clinical Analysis ofPathogens (Basel, Switzerland) · 2026Article
- Enterococcal bacteremia in children with malignancy or after hematopoietic stem cell transplantation: real-world multicenter data from a nationwide survey in Poland (2014-2021).European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Non-traumatic necrotizing fasciitis caused by Bacillus cereus in a child with acute lymphoblastic leukemia: a case report and proposed gastrointestinal-to-hematogenous pathway.BMC infectious diseases · 2026Article
- Successful Treatment of Fournier's Gangrene in Child with Relapsed Acute Lymphoblastic Leukemia: Case Report and Review of the Literature.Infection and drug resistance · 2025Article
- Diagnostic and Therapeutic Challenge Caused byPathogens (Basel, Switzerland) · 2024Review
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46 authors at 14 institutions in 1 country.
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Abstract
The most common complications related to the treatment of childhood acute lymphoblastic leukemia (ALL) are infections. The aim of the study was to analyze the incidence and mortality rates among pediatric patients with ALL who were treated in 17 Polish pediatric hematology centers in 2020-2021 during the pandemic. Additionally, we compared these results with those of our previous study, which we conducted in the years 2012-2017. The retrospective analysis included 460 patients aged 1-18 years with newly diagnosed ALL. In our study, 361/460 (78.5%) children were reported to have microbiologically documented bacterial infections during chemotherapy. Ten patients (2.8%) died due to sepsis. Fungal infections were reported in 99 children (21.5%), of whom five (5.1%) died due to the infection. We especially observed an increase in bacterial infections during the pandemic period compared to the previous study. The directions of our actions should be to consider antibiotic prophylaxis, shorten the duration of hospitalization, and educate parents and medical staff about complications (mainly infections) during anticancer therapy. It is necessary to continue clinical studies evaluating infection prophylaxis to improve outcomes in childhood ALL patients.
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