ArticleScientific reports2023
Green synthesis and characterization of ruthenium oxide nanoparticles using Gunnera perpensa for potential anticancer activity against MCF7 cancer cells.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 12 citations in OpenAlex.
- In Vitro Anticancer Activity of Green-Synthesized Zinc Oxide Nanoparticles from Root Extract of Sida schimperiana against MDA-MB-231 Breast Cancer Cell Lines.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Bio-inspired synthesis and bio-activity of ruthenium nanoparticles from Tridax procumbens (Dagadi Pala) leaf extract.Discover nano · 2025Article
- Platinum Group Metals Nanoparticles in Breast Cancer Therapy.Pharmaceutics · 2024Review
- In-vitro cytotoxicity of biosynthesized nanoceria using Eucalyptus camaldulensis leaves extract against MCF-7 breast cancer cell line.Scientific reports · 2024Article
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
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Abstract
The use of green methods for ruthenium oxide nanoparticles (RuONPs) synthesis is gaining attention due to their eco-friendliness, cost-effectiveness, and availability. However, reports on the green synthesis and characterization of RuONPs are limited compared to other metal nanoparticles. The green synthesis and characterization of RuONPs using water extracts of Gunnera perpensa leaves as a reducing agent is reported in this study. The RuONPs were characterized using X-ray diffraction (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM), and Ultraviolet spectroscopy (UV-VIS). MTT assay was used to assess the cytotoxicity of the RuONPs against MCF7 and Vero cell lines. X-ray diffraction analysis results revealed the presence of crystalline and amorphous forms of RuONPs, while IR spectroscopy revealed the presence of functional groups associated with G. perpensa leaves. SEM showed that the RuONPs consisted predominantly of hexagonal and cuboid-like structures with a considerable degree of agglomeration being observed. The cell culture results indicated a low anticancer efficacy of RuONPs against MCF7 and Vero cell lines, suggesting that RuONPs may not be a good lead for anti-cancer drugs. This study highlights the potential of using green synthesis methods to produce RuONPs and their characterization, as well as their cytotoxicity against cancer cells.
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