Evidence map›Paper›PMID 38114611›Full record

ArticleNPJ digital medicine2023

A retrospective study on machine learning-assisted stroke recognition for medical helpline calls.

Jonathan Wenstrup, Jakob Drachmann Havtorn, Lasse Borgholt, Stig Nikolaj Blomberg, Lars Maaloe, Michael R Sayre, Hanne Christensen, Christina Kruuse, Helle Collatz Christensen

Abstract read
In one paragraph

Article in NPJ digital medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Observational
  6. Words to live by: Using medic impressions to identify the need for prehospital lifesaving interventions.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jonathan Wenstrup *Department of Neurology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.ORCID http://orcid.org/0000-0001-9604-4638
Jakob Drachmann Havtorn *Corti, Store Strandstræde 21, 1255, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-4849-0817
Lasse Borgholt *Corti, Store Strandstræde 21, 1255, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-3562-8442
Stig Nikolaj BlombergPrehospital Centre Region Zealand, Ringstedgade 61, 4700, Næstved, Denmark.
Lars MaaloeCorti, Store Strandstræde 21, 1255, Copenhagen, Denmark.ORCID http://orcid.org/0000-0003-2030-520X
Michael R SayreDepartment of Emergency Medicine, University of Washington, 325 9th Ave, Box 359727, Seattle, WA, 98104, USA.ORCID http://orcid.org/0000-0003-0322-3181
Hanne ChristensenDepartment of Neurology, Copenhagen University Hospital, Bispebjerg, Bispebjerg Bakke 23, 2400, Copenhagen, NV, Denmark.ORCID http://orcid.org/0000-0002-7472-3194
Christina KruuseDepartment of Neurology, Copenhagen University Hospital, Herlev and Gentofte, Borgmester Ib Juuls Vej 1, 2730, Herlev, Denmark.
Helle Collatz ChristensenPrehospital Centre Region Zealand, Ringstedgade 61, 4700, Næstved, Denmark. hcli@regionsjaelland.dk.ORCID http://orcid.org/0000-0003-3302-7149

Funding

Innovationsfonden (Innovation Fund Denmark) 0153-00167BInnovationsfonden (Innovation Fund Denmark) 2051-00015BNovo Nordisk Fonden (Novo Nordisk Foundation) NNF18OC0031840
6 · The paper itself

Abstract

Advanced stroke treatment is time-dependent and, therefore, relies on recognition by call-takers at prehospital telehealth services to ensure fast hospitalisation. This study aims to develop and assess the potential of machine learning in improving prehospital stroke recognition during medical helpline calls. We used calls from 1 January 2015 to 31 December 2020 in Copenhagen to develop a machine learning-based classification pipeline. Calls from 2021 are used for testing. Calls are first transcribed using an automatic speech recognition model and then categorised as stroke or non-stroke using a text classification model. Call-takers achieve a sensitivity of 52.7% (95% confidence interval 49.2-56.4%) with a positive predictive value (PPV) of 17.1% (15.5-18.6%). The machine learning framework performs significantly better (p < 0.0001) with a sensitivity of 63.0% (62.0-64.1%) and a PPV of 24.9% (24.3-25.5%). Thus, a machine learning framework for recognising stroke in prehospital medical helpline calls may become a supportive tool for call-takers, aiding in early and accurate stroke recognition.

Identifiers

PMID38114611
PMCPMC10730829

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.