Evidence map›Paper›PMID 38113981›Full record

ArticleAnalytical biochemistry2024

An assessment of a biosensor system for the quantification of microcystins in freshwater cyanobacterial blooms.

Justin D Chaffin, Katelyn B Barker, Sarah R Bickman, John F Bratton, Thomas B Bridgeman, Mudit Bhatia, Seth D Buchholz, George S Bullerjahn, Thomas H Johengen, Dae-Wook Kang and 13 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical biochemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Toxins · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Justin D ChaffinF.T. Stone Laboratory and Ohio Sea Grant, The Ohio State University, Put in Bay, Ohio 43456, USA; Bowling Green State University, Bowling Green, Ohio 43403, USA. Electronic address: chaffin.46@osu.edu.
Katelyn B BarkerBowling Green State University, Bowling Green, Ohio 43403, USA.
Sarah R BickmanLightDeck Diagnostics, Inc., 5603 Arapahoe Ave, Boulder, Colorado 80303, USA.
John F BrattonLimnoTech, Inc. 501 Avis Dr., Ann Arbor Michigan 48108, USA.
Thomas B BridgemanLake Erie Center, The University of Toledo, Oregon, Ohio 43616, USA.
Mudit BhatiaDepartment of Civil and Environmental Engineering, University of Toledo, 3006 Nitschke Hall, Toledo, Ohio 43606, USA.
Seth D BuchholzBowling Green State University, Bowling Green, Ohio 43403, USA.
George S BullerjahnBowling Green State University, Bowling Green, Ohio 43403, USA.
Thomas H JohengenCooperative Institute for Great Lakes Research, University of Michigan, Ann Arbor, Michigan 48109, USA.
Dae-Wook KangDepartment of Civil and Environmental Engineering, University of Toledo, 3006 Nitschke Hall, Toledo, Ohio 43606, USA.
Gregory G LewisLightDeck Diagnostics, Inc., 5603 Arapahoe Ave, Boulder, Colorado 80303, USA.
Michael J LochheadLightDeck Diagnostics, Inc., 5603 Arapahoe Ave, Boulder, Colorado 80303, USA.
Brooks M MacdonaldLightDeck Diagnostics, Inc., 5603 Arapahoe Ave, Boulder, Colorado 80303, USA.
Cassandra L PetrouLightDeck Diagnostics, Inc., 5603 Arapahoe Ave, Boulder, Colorado 80303, USA.
Michelle PlatzLimnoTech, Inc. 501 Avis Dr., Ann Arbor Michigan 48108, USA.
Heidi PurcellCooperative Institute for Great Lakes Research, University of Michigan, Ann Arbor, Michigan 48109, USA.
Jack RoserLightDeck Diagnostics, Inc., 5603 Arapahoe Ave, Boulder, Colorado 80303, USA.
Youngwoo SeoDepartment of Civil and Environmental Engineering, University of Toledo, 3006 Nitschke Hall, Toledo, Ohio 43606, USA; Department of Chemical Engineering, University of Toledo, 3048 Nitschke Hall, Toledo, Ohio 43606, USA.
Mashuk SiddiqueeDepartment of Civil and Environmental Engineering, University of Toledo, 3006 Nitschke Hall, Toledo, Ohio 43606, USA.
Brenda SnyderLake Erie Center, The University of Toledo, Oregon, Ohio 43616, USA.
Autumn T TaylorF.T. Stone Laboratory and Ohio Sea Grant, The Ohio State University, Put in Bay, Ohio 43456, USA.
Edward M VerhammeLimnoTech, Inc. 501 Avis Dr., Ann Arbor Michigan 48108, USA.
Judy A WestrickLumigen Instrument Center, Wayne State University, 5101Cass Ave., Detroit, Michigan 48202, USA.

Funding

Research Experience & Training Coordination CoreP42ES030991 · NIEHS · WAYNE STATE UNIVERSITY · PI Andrea E Cassidy-Bushrow · 2022 to 2026
$13.9M
Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2014 to 2021
$10.1M
Translational Research Support CoreP30ES036084 · NIEHS · WAYNE STATE UNIVERSITY · PI Melissa A Runge-Morris · 2024 to 2026
$5.2M
The synergistic effects of climate and anthropogenic drivers on toxic cyanobacterial bloomsP01ES028939 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Gregory James Dick, David Joseph Kennedy · 2018 to 2026
$3.7M
NIEHS NIH HHS P30 ES020957NIEHS NIH HHS P30 ES036084NIEHS NIH HHS P42 ES030991
6 · The paper itself

Abstract

Microcystin-producing cyanobacterial blooms are a global issue threatening drinking water supplies and recreation on lakes and beaches. Direct measurement of microcystins is the only way to ensure waters have concentrations below guideline concentrations; however, analyzing water for microcystins takes several hours to days to obtain data. We tested LightDeck Diagnostics' bead beater cell lysis and two versions of the quantification system designed to give microcystin concentrations within 20 min and compared it to the standard freeze-thaw cycle lysis method and ELISA quantification. The bead beater lyser was only 30 % effective at extracting microcystins compared to freeze-thaw. When considering freeze-thaw samples analyzed in 2021, there was good agreement between ELISA and LightDeck version 2 (n = 152; R

Indexed as

Biosensing TechniquesCyanobacteriaHarmful Algal BloomLakesMicrocystinsmicrocystinMicrocystinsCyanotoxinsELISAHarmful algal bloomLake ErieMicrocystisPlanktothrix

Identifiers

PMID38113981
PMCPMC12869536

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.