Evidence map›Paper›PMID 38113856›Full record

ArticleLupus2024

Non-pharmacological rehabilitation interventions for individuals with antiphospholipid syndrome: A scoping review.

Alexandra E Harper, Yen T Chen, Stephanie Tancer, Kyla R Rodgers, Amber D Crumb, Whitney A Townsend, Jason S Knight, Susan L Murphy

Open access · greenAbstract readCase ReportsScoping Review
In one paragraph

Article in Lupus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alexandra E HarperDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-0623-3879
Yen T ChenDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Stephanie TancerDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Kyla R RodgersDepartment of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Amber D CrumbUniversity of Michigan Antiphospholipid Syndrome Program, Ann Arbor, MI, USA.
Whitney A TownsendTaubman Health Sciences Library, University of Michigan, Ann Arbor, MI, USA.
Jason S KnightUniversity of Michigan Antiphospholipid Syndrome Program, Ann Arbor, MI, USA.
Susan L MurphyDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
University of Michigan · US

Funding

TRAINING OF ARTHRITIS RESEARCH SCIENTISTST32AR007080 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jason Knight · 1986 to 2026
$6.3M
ACL HHS 90ARCP0003NIAMS NIH HHS T32 AR007080
6 · The paper itself

Abstract

objectiveThe objective of this study was to explore what non-pharmacological interventions have been examined for individuals with antiphospholipid syndrome (APS).

methodsWe conducted a systematic literature search of the databases PubMed, Embase, Scopus, Web of Science, CINAHL, and ClinicalTrials.gov from 1983-Feb. 2023. Our scoping review included studies that examined non-pharmacological interventions for individuals with APS using patient-reported outcome measures. We excluded studies that reported physiological outcomes only.

resultsThe review yielded one case study on the safety and efficacy of an exercise program for a 15-year-old male with secondary APS using physiological and patient-reported outcome measures. Despite the lack of evidence of non-pharmacological interventions for individuals with APS, one excluded study reported that individuals with APS want guidance about physical activity and exercise. We also found several types of potentially relevant non-pharmacological interventions for individuals with lupus, a disease that often co-occurs with APS.

conclusionsNon-pharmacological interventions may offer a solution for addressing some non-thrombotic or non-obstetric APS symptoms, such as neurological, physical, and cognitive symptoms that are not well-controlled by anticoagulation. Due to the unique risks associated with APS, research is needed to determine the safety and efficacy of non-pharmacological interventions, particularly those involving exercise. Adopting a comprehensive, multidisciplinary approach to managing patients with APS and involving rehabilitation professionals, who are experts in the design and delivery of non-pharmacological interventions, may provide a foundation for developing and testing novel interventions that improve health outcomes while also fulfilling unmet needs reported by patients.

Indexed as

Antiphospholipid SyndromeAdolescentExerciseExercise TherapyHumansMalePatient Reported Outcome MeasuresAntiphospholipid syndromerehabilitationsystematic review

Identifiers

PMID38113856
PMCPMC11003253
OpenAlexW4389933005

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.