Evidence map›Paper›PMID 38113236›Full record

ArticlePLoS biology2023

Pituitary-immune bidirectional crosstalk under systemic inflammation.

Qingyun Li

Abstract readComment
In one paragraph

Article in PLoS biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Qingyun LiDepartment of Neuroscience, Department of Genetics, Hope Center for Neurological Disorders, Center for Brain Immunology and Glia, Washington University in St. Louis School of Medicine, St. Louis, Missouri, United States of America.ORCID 0000-0002-3457-5967

Funding

Dissecting the origin, regulation and function of microglial subsets in Alzheimer's diseaseR01AG078512 · NIA · WASHINGTON UNIVERSITY · PI Qingyun Li · 2023 to 2026
$2.2M
NIA NIH HHS R01 AG078512
6 · The paper itself

Abstract

The pituitary gland responds to and modulates immune stress through the hypothalamus-pituitary-adrenal axis. A new study in PLOS Biology reveals unconventional bidirectional communication between hormone-producing cells and the immune system upon systemic inflammation.

Indexed as

Hypothalamo-Hypophyseal SystemPituitary GlandGene Expression ProfilingHormonesHumansInflammationHormones

Identifiers

PMID38113236
PMCPMC10729977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.