Evidence map›Paper›PMID 38113202›Full record

ArticlePloS one2023

Associations between specialty care and improved outcomes among patients with diabetic foot ulcers.

Yingzhou Liu, Menggang Yu, Jamie N LaMantia, Jennifer Mason Lobo, Justin J Boutilier, Yao Liu, Meghan B Brennan

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yingzhou LiuDepartment of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.
Menggang YuDepartment of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.
Jamie N LaMantiaDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.
Jennifer Mason LoboDepartment of Public Health Sciences, University of Virginia, Charlottesville, Virginia, United States of America.ORCID 0000-0001-8375-2475
Justin J BoutilierDepartment of Industrial and Systems Engineering, College of Engineering, University of Wisconsin, Madison, Wisconsin, United States of America.
Yao LiuDepartment of Ophthalmology and Visual Sciences, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.
Meghan B BrennanDepartment of Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, United States of America.ORCID 0000-0002-2316-4150
University of Wisconsin–Madison · USUniversity of Virginia · US

Funding

Crossing the divide: piloting an integrated care model to bridge rural-urban healthcare systems and reduce major amputations among rural patients with diabetic foot ulcersR01DK132569 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI BRENNAN, MEGHAN · 2022 to 2024
$921k
AHRQ HHS K08 HS026279NIDDK NIH HHS R01 DK132569
6 · The paper itself

Abstract

objectiveSpecialty care may improve diabetic foot ulcer outcomes. Medically underserved populations receive less specialty care. We aimed to determine the association between specialty care and ulcer progression, major amputation, or death. If a beneficial association is found, increasing access to specialty care might help advance health equity. RESEARCH DESIGN AND

methodsWe retrospectively analyzed a cohort of Wisconsin and Illinois Medicare patients with diabetic foot ulcers (n = 55,409), stratified by ulcer severity (i.e., early stage, osteomyelitis, or gangrene). Within each stratum, we constructed Kaplan-Meier curves for event-free survival, defining events as: ulcer progression, major amputation, or death. Patients were grouped based on whether they received specialty care from at least one of six disciplines: endocrinology, infectious disease, orthopedic surgery, plastic surgery, podiatry, and vascular surgery. Multivariate Cox proportional hazard models estimated the association between specialty care and event-free survival, adjusting for sociodemographic factors and comorbidities, and stratifying on ulcer severity.

resultsPatients who received specialty care had longer event-free survival compared to those who did not (log-rank p<0.001 for all ulcer severity strata). After adjusting, receipt of specialty care, compared to never, remained associated with improved outcomes for all ulcer severities (early stage adjusted hazard ratio 0.34, 95% CI 0.33-0.35, p<0.001; osteomyelitis aHR 0.22, 95% CI 0.20-0.23, p<0.001; gangrene aHR 0.22, 95% CI 0.20-0.24, p<0.001).

conclusionsSpecialty care was associated with longer event-free survivals for patients with diabetic foot ulcers. Increased, equitable access to specialty care might improve diabetic foot ulcer outcomes and disparities.

Indexed as

Diabetes MellitusDiabetic FootOsteomyelitisAgedGangreneHumansMedicareRetrospective StudiesUnited States

Identifiers

PMID38113202
PMCPMC10729988
OpenAlexW4390016164

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.