ArticleJournal of medical Internet research2023
Evaluation of the Current State of Chatbots for Digital Health: Scoping Review.
Article in Journal of medical Internet research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Efficacy, User Engagement, and Acceptability of Cognitive Behavioral Therapy-Oriented Psychological Chatbots for Adults With Depressive and/or Anxiety Symptoms: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Smartphone-Based Digital Health Interventions: A Comprehensive Systematic Review of Efficacy for Cardiovascular and Cerebrovascular Outcomes.Journal of medical systems · 2025Pooled it
- Effectiveness of stage-of-change (SOC)-tailored interventions in increasing uptake of any type of vaccination: A systematic review and meta-analysis.Applied psychology. Health and well-being · 2025Pooled it
- The Impact of Chatbot Type and Normative Messaging on Chatbot Usage Intention Based on the Health Technology Acceptance Model: Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Chatbot-Delivered Real-Time Support to Improve HIV Self-Testing Rates: A Randomized Clinical Trial.JAMA network open · 2025Trial
- Weight Loss and Engagement Among Active Users of a Dietitian-Led Digital Nutrition Platform: Retrospective Cohort Study.JMIR mHealth and uHealth · 2026Article
- An Acceptance Criteria Framework for Determining the Implementation Fit of Custom Large Language Models in Public Health Interventions.Journal of medical Internet research · 2026Article
- Engagement with a Chatbot-based Intervention for the delivery of mailed at-home COVID-19 Testing: a Descriptive Log Analysis Study from the SCALE-UP II Trial.medRxiv : the preprint server for health sciences · 2026Article
- Enhancing patient care with AI agents: integrating advanced chatbot technologies for improved healthcare delivery.BMC medical informatics and decision making · 2026Article
- Artificial intelligence-based chatbots to enhance medication adherence among patients with non-communicable chronic diseases: Systematic review and meta-analysis.PLOS digital health · 2026Article
- Can Medical Chatbots Trigger Disinhibition and Encourage Health Information Disclosure?Healthcare (Basel, Switzerland) · 2026Article
- Engagement-quality mismatch in robot-assisted total knee arthroplasty short videos on TikTok and Bilibili.Journal of robotic surgery · 2026Article
- It Is the Journey, Not the Destination: Moving From End Points to Trajectories When Assessing Chatbot Mental Health Safety.JMIR mental health · 2026Article
- Artificial intelligence for clinical trial design, conduct, and analysis: a narrative review.ESMO real world data and digital oncology · 2026Review
- GARDE-Chat: a scalable, open-source platform for building and deploying health chatbots.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- Engaging Artificial Intelligence (AI)-based chatbots in digital health: A systematic review.PLOS digital health · 2026Article
- Toward clinical integration of generative AI in mental health: personalization, multimodality and inter-entity experience.Frontiers in public health · 2026Article
- Mapping applications and evaluations of LLM-enabled AI chatbots for health purposes: a scoping review.Frontiers in public health · 2026Article
- Article
- Chatbots as frontline educators in sexual reproductive health rights: evidence, limitations, and ethical considerations.Frontiers in digital health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChatbots have become ubiquitous in our daily lives, enabling natural language conversations with users through various modes of communication. Chatbots have the potential to play a significant role in promoting health and well-being. As the number of studies and available products related to chatbots continues to rise, there is a critical need to assess product features to enhance the design of chatbots that effectively promote health and behavioral change.
objectiveThis scoping review aims to provide a comprehensive assessment of the current state of health-related chatbots, including the chatbots' characteristics and features, user backgrounds, communication models, relational building capacity, personalization, interaction, responses to suicidal thoughts, and users' in-app experiences during chatbot use. Through this analysis, we seek to identify gaps in the current research, guide future directions, and enhance the design of health-focused chatbots.
methodsFollowing the scoping review methodology by Arksey and O'Malley and guided by the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) checklist, this study used a two-pronged approach to identify relevant chatbots: (1) searching the iOS and Android App Stores and (2) reviewing scientific literature through a search strategy designed by a librarian. Overall, 36 chatbots were selected based on predefined criteria from both sources. These chatbots were systematically evaluated using a comprehensive framework developed for this study, including chatbot characteristics, user backgrounds, building relational capacity, personalization, interaction models, responses to critical situations, and user experiences. Ten coauthors were responsible for downloading and testing the chatbots, coding their features, and evaluating their performance in simulated conversations. The testing of all chatbot apps was limited to their free-to-use features.
resultsThis review provides an overview of the diversity of health-related chatbots, encompassing categories such as mental health support, physical activity promotion, and behavior change interventions. Chatbots use text, animations, speech, images, and emojis for communication. The findings highlight variations in conversational capabilities, including empathy, humor, and personalization. Notably, concerns regarding safety, particularly in addressing suicidal thoughts, were evident. Approximately 44% (16/36) of the chatbots effectively addressed suicidal thoughts. User experiences and behavioral outcomes demonstrated the potential of chatbots in health interventions, but evidence remains limited.
conclusionsThis scoping review underscores the significance of chatbots in health-related applications and offers insights into their features, functionalities, and user experiences. This study contributes to advancing the understanding of chatbots' role in digital health interventions, thus paving the way for more effective and user-centric health promotion strategies. This study informs future research directions, emphasizing the need for rigorous randomized control trials, standardized evaluation metrics, and user-centered design to unlock the full potential of chatbots in enhancing health and well-being. Future research should focus on addressing limitations, exploring real-world user experiences, and implementing robust data security and privacy measures.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.