ArticleeLife2023
Myomatrix arrays for high-definition muscle recording.
Abstract read
In one paragraph
Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed.
- Article
- Polarized mitochondrial respiratory chain complexes in synaptic mitochondria induced by plasticity signals.Molecular and cellular biochemistry · 2026Article
- Reinnervation of Muscle Targets Enhances the Separability of Motor Unit Signals Following Peripheral Nerve Transfers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- High performance sorting of motor unit action potentials with EMUsort.bioRxiv : the preprint server for biology · 2026Article
- Muscle spindles provide flexible sensory feedback for movement sequences.Cell reports · 2025Article
- Spinal interneuron population dynamics underlying flexible pattern generation.Nature communications · 2025Article
- Motor unit mechanisms of speed control in mouse locomotion.bioRxiv : the preprint server for biology · 2025Article
- A galanin-positive population of lumbar spinal cord neurons modulates sexual arousal and copulatory behavior in male mice.Nature communications · 2025Article
- Neurobiology of Dystonia: Review of Genetics, Animal Models, and Neuroimaging.Brain sciences · 2025Review
- Motor unit adaptation to disuse: crossing the threshold from firing rate suppression to neuromuscular junction transmission.The Journal of physiology · 2025Review
- An update on spinal cord injury and diaphragm neuromotor control.Expert review of respiratory medicine · 2025Review
- JiSuJi, a virtual muscle for small animal simulations, accurately predicts force from naturalistic spike trains.bioRxiv : the preprint server for biology · 2025Article
- A novel biomechanical model of the proximal mouse forelimb predicts muscle activity in optimal control simulations of reaching movements.Journal of neurophysiology · 2025Article
- A Simple, Low-Cost Implant for Reliable Diaphragm EMG Recordings in Awake, Behaving Rats.eNeuro · 2025Article
- Impedance, postural and dynamic force controls in motor Pool recruitment - new isometric findings and future questions.Journal of neurophysiology · 2024Article
- Hand-Jaw Coordination as Mice Handle Food Is Organized around Intrinsic Structure-Function Relationships.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Article
- An output-null signature of inertial load in motor cortex.Nature communications · 2024Article
- Accessing populations of motor units.eLife · 2024Article
Corrections and comments
- Update of
Authors and funding
52 authors.
Bryce Chung *Department of Biology, Emory University, Atlanta, United States.
Muneeb Zia *School of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, United States.
Kyle A ThomasGraduate Program in Biomedical Engineering at Emory University and Georgia Tech, Atlanta, United States.
Jonathan A MichaelsDepartment of Physiology and Pharmacology, Western University, London, Canada.ORCID 0000-0002-5179-3181
Amanda JacobDepartment of Biology, Emory University, Atlanta, United States.
Andrea PackNeuroscience Graduate Program, Emory University, Atlanta, United States.
Matthew J WilliamsGraduate Program in Biomedical Engineering at Emory University and Georgia Tech, Atlanta, United States.
Kailash NagapudiDepartment of Biology, Emory University, Atlanta, United States.
Lay Heng TengDepartment of Biology, Emory University, Atlanta, United States.
Eduardo ArrambideDepartment of Biology, Emory University, Atlanta, United States.
Logan OuelletteDepartment of Biology, Emory University, Atlanta, United States.
Nicole OeyDepartment of Biology, Emory University, Atlanta, United States.
Rhuna GibbsDepartment of Biology, Emory University, Atlanta, United States.
Philip AnschutzGraduate Program in BioEngineering, Georgia Tech, Atlanta, United States.
Jiaao LuGraduate Program in Electrical and Computer Engineering, Georgia Tech, Atlanta, United States.ORCID 0000-0002-7973-1679
Yu WuSchool of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, United States.
Mehrdad KashefiDepartment of Physiology and Pharmacology, Western University, London, Canada.ORCID 0000-0001-5981-5923
Tomomichi OyaDepartment of Physiology and Pharmacology, Western University, London, Canada.ORCID 0000-0003-1233-6356
Rhonda KerstenDepartment of Physiology and Pharmacology, Western University, London, Canada.
Alice C MosbergerZuckerman Mind Brain Behavior Institute at Columbia University, New York, United States.ORCID 0000-0003-1114-1469
Sean O'ConnellGraduate Program in Biomedical Engineering at Emory University and Georgia Tech, Atlanta, United States.
Runming WangDepartment of Biomedical Engineering at Emory University and Georgia Tech, Atlanta, United States.
Hugo MarquesChampalimaud Neuroscience Programme, Champalimaud Foundation, Lisbon, Portugal.ORCID 0000-0002-8709-4841
Ana Rita MendesChampalimaud Neuroscience Programme, Champalimaud Foundation, Lisbon, Portugal.
Constanze LenschowChampalimaud Neuroscience Programme, Champalimaud Foundation, Lisbon, Portugal.
Gayathri KondakathDepartment of Biology, Tufts University, Medford, United States.
Jeong Jun KimSolomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, United States.
William OlsonSolomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, United States.
Kiara N QuinnDepartments of Biomedical Engineering and Neurology, Johns Hopkins School of Medicine, Baltimore, United States.
Pierce PerkinsDepartments of Biomedical Engineering and Neurology, Johns Hopkins School of Medicine, Baltimore, United States.
Graziana GattoSalk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0002-4244-8925
Ayesha ThanawallaSalk Institute for Biological Studies, La Jolla, United States.
Susan ColtmanDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, United States.
Taegyo KimDepartment of Neurobiology & Anatomy, Drexel University, College of Medicine, Philadelphia, United States.
Trevor SmithDepartment of Neurobiology & Anatomy, Drexel University, College of Medicine, Philadelphia, United States.
Ben Binder-MarkeyDepartment of Physical Therapy and Rehabilitation Sciences, Drexel University College of Nursing and Health Professions, Philadelphia, United States.ORCID 0000-0001-8920-4381
Martin ZabackDepartment of Health and Rehabilitation Sciences, Temple University, Philadelphia, United States.
Christopher K ThompsonDepartment of Health and Rehabilitation Sciences, Temple University, Philadelphia, United States.
Simon GiszterDepartment of Neurobiology & Anatomy, Drexel University, College of Medicine, Philadelphia, United States.
Abigail PersonDepartment of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, United States.ORCID 0000-0001-9805-7600
Martyn GouldingSalk Institute for Biological Studies, La Jolla, United States.
Eiman AzimSalk Institute for Biological Studies, La Jolla, United States.ORCID 0000-0002-1015-1772
Nitish ThakorDepartments of Biomedical Engineering and Neurology, Johns Hopkins School of Medicine, Baltimore, United States.
Daniel O'ConnorSolomon H. Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, United States.
Barry TrimmerDepartment of Biology, Tufts University, Medford, United States.
Susana Q LimaChampalimaud Neuroscience Programme, Champalimaud Foundation, Lisbon, Portugal.
Megan R CareyChampalimaud Neuroscience Programme, Champalimaud Foundation, Lisbon, Portugal.ORCID 0000-0002-4499-1657
Chethan PandarinathDepartment of Biomedical Engineering at Emory University and Georgia Tech, Atlanta, United States.
Rui M CostaZuckerman Mind Brain Behavior Institute at Columbia University, New York, United States.ORCID 0000-0003-1707-1051
J Andrew PruszynskiDepartment of Physiology and Pharmacology, Western University, London, Canada.ORCID 0000-0003-0786-0081
Muhannad BakirSchool of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, United States.
Samuel J SoberDepartment of Biology, Emory University, Atlanta, United States.ORCID 0000-0002-1140-7469
Funding
Spinal Circuits for the Control of Dextrous MovementU19NS112959 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI GOULDING, MARTYN D · 2019 to 2023
$14.3MMedical Scientist Training ProgramT32GM136577 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI ANDREA L COX · 2020 to 2026
$13.4MSpinal circuits for mechanical itch and light touchR35NS111643 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Martyn D Goulding · 2019 to 2026
$9.7MInterdisciplinary Engineering Career Development Center in Movement and Rehabilitation SciencesK12HD073945 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P, REINKENSMEYER, DAVID JAY · 2012 to 2021
$7.9MCrucial spinal circuit changes that mediate locomotor benefits and deficits following combined therapies after spinal cord injuryR01NS104194 · NINDS · DREXEL UNIVERSITY · PI Kimberly J Dougherty, SIMON F GISZTER · 2018 to 2026
$4.2MNorepinephrine modulation of neocortex during flexible behaviorR01NS104834 · NINDS · JOHNS HOPKINS UNIVERSITY · PI COHEN, JEREMIAH YAACOV, O'CONNOR, DANIEL HANS · 2018 to 2022
$4.1MVocal motor control and sensorimotor learning - behavior, muscles, and neuronsR01NS084844 · NINDS · EMORY UNIVERSITY · PI SOBER, SAMUEL · 2013 to 2023
$3.8MNext-Generation Tools to Measure and Manipulate Muscle Activity Across Species and BehaviorsR01NS109237 · NINDS · EMORY UNIVERSITY · PI Muhannad Bakir, Samuel Sober · 2019 to 2026
$3.8MNeural control of skilled movements: an ethological dissection of genetically tractable mammalian motor circuitsDP2NS105555 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI AZIM, EIMAN · 2017 to 2022
$3.7MCenter for Advanced Muscle BioElectronics (CAMBER)U24NS126936 · NINDS · EMORY UNIVERSITY · PI Samuel Sober · 2023 to 2026
$3.5MDefining the anatomical, molecular and functional logic of internal copy circuits involved in dexterous forelimb behaviorsR01NS111479 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI AZIM, EIMAN · 2019 to 2023
$2.9MFusing motor neuroscience and artificial intelligence to create next-generation neural prostheses.DP2NS127291 · NINDS · EMORY UNIVERSITY · PI PANDARINATH, CHETHAN · 2021 to 2024
$2.4MCIHR PJT-175010European Research Council 772827European Research Council 866237NIBIB NIH HHS R01 EB022872NIBIB NIH HHS R01EB022872NICHD NIH HHS K12 HD073945NIDCR NIH HHS F31 DE033256NIGMS NIH HHS T32 GM136577NIH HHS DP2NS127291NIH HHS K12HD073945NIMH NIH HHS F32 MH120873NIMH NIH HHS F32MH120873NINDS NIH HHS DP2 NS105555NINDS NIH HHS DP2NS105555NINDS NIH HHS DP2 NS127291NINDS NIH HHS F31 NS124347NINDS NIH HHS F31NS124347NINDS NIH HHS K99 NS126307NINDS NIH HHS K99NS126307NINDS NIH HHS R01 NS084844NINDS NIH HHS R01NS084844NINDS NIH HHS R01 NS099375NINDS NIH HHS R01 NS104194NINDS NIH HHS R01NS104194NINDS NIH HHS R01 NS104834NINDS NIH HHS R01NS104834NINDS NIH HHS R01 NS109237NINDS NIH HHS R01NS109237NINDS NIH HHS R01 NS111479NINDS NIH HHS R01NS111479NINDS NIH HHS R01NS111643NINDS NIH HHS R01NS112959NINDS NIH HHS R01 NS124820NINDS NIH HHS R01NS124820NINDS NIH HHS R34 NS118412NINDS NIH HHS R34NS118412NINDS NIH HHS R35 NS111643NINDS NIH HHS RF1 NS128898NINDS NIH HHS RF1NS128898NINDS NIH HHS U19 NS112959NINDS NIH HHS U19NS112959NINDS NIH HHS U24 NS126936NINDS NIH HHS U24NS126936Swiss National Science Foundation P2EZP3_172128Swiss National Science Foundation P400PM_183904
Abstract
Neurons coordinate their activity to produce an astonishing variety of motor behaviors. Our present understanding of motor control has grown rapidly thanks to new methods for recording and analyzing populations of many individual neurons over time. In contrast, current methods for recording the nervous system's actual motor output - the activation of muscle fibers by motor neurons - typically cannot detect the individual electrical events produced by muscle fibers during natural behaviors and scale poorly across species and muscle groups. Here we present a novel class of electrode devices ('Myomatrix arrays') that record muscle activity at unprecedented resolution across muscles and behaviors. High-density, flexible electrode arrays allow for stable recordings from the muscle fibers activated by a single motor neuron, called a 'motor unit,' during natural behaviors in many species, including mice, rats, primates, songbirds, frogs, and insects. This technology therefore allows the nervous system's motor output to be monitored in unprecedented detail during complex behaviors across species and muscle morphologies. We anticipate that this technology will allow rapid advances in understanding the neural control of behavior and identifying pathologies of the motor system.
Indexed as
Motor NeuronsPrimatesAnimalsElectrodesMiceMuscle Fibers, SkeletalRatsBengalese finchelectrodeEMGfroghawk mothmotor systemsmouseneuroscienceratrhesus macaque
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.