Evidence map›Paper›PMID 38112926›Full record

ReviewStem cell reviews and reports2024

Sorting Technology for Mesenchymal Stem Cells from a Single Tissue Source.

Xinyi Feng, Fangfang Qi, Hailin Wang, Wenzhen Li, Yuyang Gan, Caiyu Qi, Zhen Lin, Lu Chen, Piao Wang, Zhiqi Hu and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Stem cell reviews and reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xinyi Feng *The First Clinical School of Southern Medical University, Guangzhou, China.
Fangfang Qi *Department of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, China.
Hailin WangDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, China.
Wenzhen LiDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, China.
Yuyang GanDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, China.
Caiyu QiThe First Clinical School of Southern Medical University, Guangzhou, China.
Zhen LinDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, China.
Lu ChenDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, China.
Piao WangDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, China.
Zhiqi HuDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, China. huzhiqidr163@i.smu.edu.ORCID 0000-0002-1657-0396
Yong MiaoDepartment of Plastic and Aesthetic Surgery, Nanfang Hospital of Southern Medical University, Guangzhou, China. miaoyong123@i.smu.edu.cn.ORCID 0000-0003-4254-0673

Funding

Guangzhou Municipal Science and Technology Bureau SL2022A04J02027National Natural Science Foundation of China Grant No.81772104, No.81701929, No.81971889, No.81902013, No.82003085, No.82202468Natural Science Foundation of Guangdong Province Grant No.2017A030310120, Grant No.2019A1515012170
6 · The paper itself

Abstract

Mesenchymal stem cells (MSCs) are adult stem cells that can be obtained, enriched and proliferated in vitro. They owned enormous potential in fields like regenerative medicine, tissue engineering and immunomodulation. However, though isolated from the same origin, MSCs are still essentially heterogeneous cell populations with different phenotypes and functions. This heterogeneity of MSCs significantly affects their therapeutic efficacy and brings obstacles to scientific research. Thus, reliable sorting technology which can isolate or purify MSC subpopulations with various potential and differentiation pathways is urgently needed. This review summarized principles, application status and clinical implications for these sorting methods, aiming at improving the understanding of MSC heterogeneity as well as providing fresh perspectives for subsequent clinical applications.

Indexed as

Adult Stem CellsMesenchymal Stem CellsCell DifferentiationRegenerative MedicineTissue EngineeringBiotechnologyCell heterogeneityCell sortingStem cells

Identifiers

PMID38112926

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.