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ArticlePulmonary therapy2024

Delphi Consensus on Clinical Applications of GOLD 2023 Recommendations in COPD Management: How Aligned are Recommendations with Clinical Practice?

Antonio Anzueto, Mark Cohen, Andres L Echazarreta, Gehan Elassal, Irma Godoy, Rafael Paramo, Abdullah Sayiner, Carlos A Torres-Duque, Sudeep Acharya, Bhumika Aggarwal and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pulmonary therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 7 countries.

Antonio AnzuetoUniversity of Texas Health and South Texas Veterans Health Care System, San Antonio, TX, USA. anzueto@uthscsa.edu.
Mark CohenHospital Centro Medico, Guatemala City, Guatemala.
Andres L EchazarretaRespiratory Unit, Centro Médico Capital, La Plata, Argentina.
Gehan ElassalDepartment of Pulmonology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Irma GodoyDepartment of Internal Medicine, Botucatu Medical School, UNESP - Univ Estadual Paulista, Botucatu Campus, Pneumology Area, São Paulo, Brazil.
Rafael ParamoUniversidad Anáhuac, Querétaro, México.
Abdullah SayinerDepartment of Chest Diseases, Faculty of Medicine, Ege University, Izmir, Turkey.
Carlos A Torres-DuqueCINEUMO, Research Center, Fundación Neumológica Colombiana, Bogotá, Colombia.
Sudeep AcharyaEmerging Markets, GSK, Singapore, Singapore.
Bhumika AggarwalEmerging Markets, GSK, Singapore, Singapore.
Hakan ErkusEmerging Markets, GSK, Istanbul, Turkey.
Gur LevyEmerging Markets, GSK, Panama City, Panama.
Ain Shams University · EGEge University · TRFundación Neumológica Colombiana · COThe University of Texas Health Science Center at San Antonio · USUnidad de Cirugía Cardiovascular de Guatemala · GTUniversidad Anáhuac Querétaro · MXUniversidade Estadual Paulista (Unesp) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe objective of this Delphi study was to understand and assess the level of consensus among respiratory experts on the clinical application of GOLD 2023 recommendations in management of patients with chronic obstructive pulmonary disease (COPD).

methodsThe study comprised two online surveys and a participant meeting with 34 respiratory experts from 16 countries. Responses of 73 questions were recorded using a Likert scale ranging from 0 (disagreement) to 9 (agreement). The consensus threshold was 75%.

resultsSurvey 1 and survey 2 had 34 and 32 participants, respectively; and 25 attended the participant meeting. Consensus was reached on survey 1: 28/42; survey 2: 18/30 close-ended questions. A consensus was reached on the clinical relevance of most updates in definitions and diagnosis of COPD. Mixed results for the treatment recommendations by GOLD were noted: 74% agreed with the recommendation to initiate treatment with dual bronchodilators for group E patients; 63% agreed for including inhaled corticosteroids (ICS)/long-acting β

conclusionsThis Delphi study demonstrated a high level of consensus regarding key concepts of GOLD 2023 report, with most participants favoring recent updates in definitions, diagnosis, management, and prevention of COPD. More evidence on the etiotype based management and treatment options for group B and E are required which could further strengthen clinical application of the GOLD report.

Indexed as

Clinical practiceCOPDDelphi procedureGOLD 2023

Identifiers

PMID38112909
PMCPMC10881920
OpenAlexW4389946135

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.