ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2024
Do physical fitness and cognitive function mediate the relationship between basic activities of daily living and quality of life in older adults with dementia?
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06637228 (Effects of Integrated Exercise on Sarcopenia, Depression Symptoms, and Quality of Life of Community-Dwelling Older Adults With Dementia), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of Integrated Exercise on Sarcopenia, Depression Symptoms, and Quality of Life of Community-Dwelling Older Adults With Dementia
Who cites it
5 citing papers in PubMed.
- The Role of Subjective Vitality Among Older Adults from a Self-Determination Theory Perspective: A Scoping Review.Geriatrics (Basel, Switzerland) · 2026Review
- The Intersection of Physical Inactivity, Dementia, and Gender: A Population-Based Study of All-Cause Mortality in Middle-Aged and Older Adults in Korea.Medicina (Kaunas, Lithuania) · 2026Article
- Calibrating limitation features and dependence levels in basic activities of daily living among individuals with dementia: an item response theory-based analysis.BMC geriatrics · 2026Article
- Association Between Lower-Limb Muscle Quality, Cognitive Function and Sarcopenia in Older Adults: Cross-Sectional Study.Bioengineering (Basel, Switzerland) · 2026Article
- Cognition, Physical Performance, and Fall-Related Mobility Outcomes in Healthy Older Adults: A Cross-Sectional Study.Sports (Basel, Switzerland) · 2025Article
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Authors and funding
5 authors.
Funding
Abstract
purposeIndependence in activities of daily living (ADLs) is associated with quality of life (QoL) in individuals with dementia. However, the contribution of physical and cognitive functions to this relationship needs further examination. This study aims to examine the mediating effect of physical fitness and cognitive function in the relationship between independence in basic ADLs and QoL among older adults with dementia.
methodsThis cross-sectional study included 107 older adults with dementia (74.8% women; age 78.21 ± 7.70 years). Independence in basic ADL and QoL were evaluated using the Barthel Index (BI) and QoL- Alzheimer's Disease Scale, respectively. The Alzheimer's Disease Assessment Scale-Cognitive Subscale and the Mini-Mental State Examination were applied to assess cognitive function. Physical fitness was evaluated using the 30-s chair stand, 2-min step and the Timed-Up and Go tests. A structural equation modelling (SEM) with bootstrapping estimation was conducted to determine the relationship between all variables.
resultsIndependence in basic ADL positively affected QoL and this association was mediated by physical fitness (β = 0.242, p = 0.011). No statistically significant results were observed when testing cognitive function as a mediator between BI and QoL (β = 0.009, p = 0.345).
conclusionsPhysical fitness (i.e., lower body strength, aerobic capacity, and mobility) plays a role in the relationship between basic ADL independence and QoL of older adults with dementia, reinforcing the need to improve and monitor these parameters throughout the disease progression. Future longitudinal studies should explore the temporal relationship between physical and cognitive function and its contribution to basic ADL independence and QoL.
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