Evidence map›Paper›PMID 38112761›Full record

ArticleEuropean journal of nutrition2024

Association between vitamin D deficiency and post-acute outcomes of SARS-CoV-2 infection.

Jheng-Yan Wu, Mei-Yuan Liu, Wan-Hsuan Hsu, Ya-Wen Tsai, Ting-Hui Liu, Po-Yu Huang, Min-Hsiang Chuang, Szu-En Chin, Chih-Cheng Lai

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Article in European journal of nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. A Predictive Model for the Development of Long COVID in Children.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Jheng-Yan Wu *Department of Nutrition, Chi Mei Medical Center, Tainan, Taiwan.
Mei-Yuan Liu *Department of Nutrition, Chi Mei Medical Center, Tainan, Taiwan.
Wan-Hsuan HsuDepartment of General Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Ya-Wen TsaiCenter of Integrative Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Ting-Hui LiuDepartment of Psychiatry, Chi Mei Medical Center, Tainan, Taiwan.
Po-Yu HuangDepartment of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Min-Hsiang ChuangDepartment of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Szu-En ChinDepartment of Surgery, Chang Gung Memorial Hospital at Chiayi, Chiayi, Taiwan.
Chih-Cheng LaiDivision of Hospital Medicine, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan. dtmed141@gmail.com.ORCID http://orcid.org/0000-0002-6334-2388
Chi Mei Medical Center · TWChiayi Chang Gung Memorial Hospital · TWChung Hwa University of Medical Technology · TWKaohsiung Medical University · TWNational Sun Yat-sen University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to investigate the association between vitamin D deficiency (VDD) and post-acute outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

methodsThis retrospective study used the TriNetX research network to identify COVID-19 patients between January 1 and November 30, 2022. Patients were matched using propensity score matching (PSM) and divided into VDD (< 20 ng/mL) and control (≥ 20 ng/mL) groups. The primary outcome was a composite of post-COVID-19 condition (identified by ICD-10 code), all-cause emergency department (ED) visits, hospitalization, and death during the follow-up period (90-180 days) after the diagnosis of COVID-19.

resultsFrom an initial recruitment of 42,674 non-hospitalized patients with COVID-19 and known 25(OH)D status, a VDD group of 8300 was identified and propensity matched with 8300 controls. During the follow-up period, the VDD group had a higher risk of the primary outcome than did the control group [hazard ratio (HR) = 1.122; 95% confidence interval (CI) = 1.041-1.210]. The VDD group also had a higher risk of all-cause ED visits (HR = 1.114; 95% CI = 1.012-1.226), all-cause hospitalization (HR = 1.230; 95% CI = 1.105-1.369), and all-cause death (HR = 1.748; 95% CI = 1.047-2.290) but not post-COVID-19 condition (HR = 0.980; 95% CI = 0.630-1.523), individually.

conclusionAmong the COVID-19 patients, VDD might be associated with a higher risk of all-cause ED visits, hospitalization, and death during the post-acute phase.

Indexed as

COVID-19Vitamin D DeficiencyEmergency Room VisitsHumansRetrospective StudiesSARS-CoV-2Vitamin DVitamin DHospitalizationLong COVIDMortalityPost-COVID-19 conditionSARS-CoV-2Vitamin D

Identifiers

PMID38112761
OpenAlexW4389948575

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.