Evidence map›Paper›PMID 38112469›Full record

ArticlemBio2024

MpaR-driven expression of an orphan terminal oxidase subunit supports

Marina K Smiley, Doran C Sekaran, Farhad Forouhar, Erica Wolin, Marko Jovanovic, Alexa Price-Whelan, Lars E P Dietrich

Open access · goldAbstract read
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Oxygen microenvironments inMicrobiology (Reading, England) · 2025
    Article
  3. A cytochromeApplied and environmental microbiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Marina K Smiley *Department of Biological Sciences, Columbia University, New York, New York, USA.
Doran C Sekaran *Department of Biological Sciences, Columbia University, New York, New York, USA.
Farhad ForouharHerbert Irving Comprehensive Cancer Center, Columbia University, New York, New York, USA.
Erica WolinDepartment of Biological Sciences, Columbia University, New York, New York, USA.
Marko JovanovicDepartment of Biological Sciences, Columbia University, New York, New York, USA.
Alexa Price-WhelanDepartment of Biological Sciences, Columbia University, New York, New York, USA.
Lars E P DietrichDepartment of Biological Sciences, Columbia University, New York, New York, USA.ORCID 0000-0003-2049-1137
Columbia University · USColumbia University Irving Medical Center · US

Funding

Integration of redox-balancing mechanisms in Pseudomonas aeruginosa biofilmsR01AI103369 · NIAID · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI DIETRICH, LARS · 2013 to 2022
$4.1M
Extensive multiplexing of protein nucleic-acid interactions to comprehensively study gene expression regulation from chromatin to mRNA degradationR01HG012216 · NHGRI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI GUTTMAN, MITCHELL, JOVANOVIC, MARKO · 2022 to 2025
$3.1M
Defining the programmed proteome rejuvenation underlying gametogenesisR01AG071869 · NIA · UNIVERSITY OF CALIFORNIA BERKELEY · PI BRAR, GLORIA ANN, JOVANOVIC, MARKO · 2021 to 2025
$2.9M
NHGRI NIH HHS R01 HG012216NIAID NIH HHS R01 AI103369NIA NIH HHS R01 AG071869
6 · The paper itself

Abstract

importanceCyanide is an inhibitor of heme-copper oxidases, which are required for aerobic respiration in all eukaryotes and many prokaryotes. This fast-acting poison can arise from diverse sources, but mechanisms by which bacteria sense it are poorly understood. We investigated the regulatory response to cyanide in the pathogenic bacterium

Indexed as

OxidoreductasesPseudomonas aeruginosaBacterial ProteinsBiofilmsCyanidesHemeRespirationBacterial ProteinsCyanidesHemeOxidoreductasesbiofilmscyanidePseudomonas aeruginosaterminal oxidasetranscriptional regulation

Identifiers

PMID38112469
PMCPMC10790758
OpenAlexW4390016441

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.