Evidence map›Paper›PMID 38112433›Full record

ArticlemSphere2024

Synergistic horizontal transfer of antibiotic resistance genes and transposons in the infant gut microbial genome.

Yanwen Ding, Xin Jiang, Jiacheng Wu, Yihui Wang, Lanlan Zhao, Yingmiao Pan, Yaxuan Xi, Guoping Zhao, Ziyun Li, Lei Zhang

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
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  7. mSystems · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yanwen Ding *Microbiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Xin Jiang *Microbiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Jiacheng WuMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yihui WangMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Lanlan ZhaoMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yingmiao PanMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Yaxuan XiMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Guoping ZhaoMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Ziyun LiMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0009-0005-1327-3168
Lei ZhangMicrobiome-X, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.ORCID 0000-0003-4284-2604
Shandong University · CN

Funding

China Postdoctoral Science Foundation (China Postdoctoral Foundation Project) Grant No. 2022M711915MOST | National Natural Science Foundation of China (NSFC) Grant No. 82172320Shandong Provincial Natural Science Foundation Grant No. ZR2022QC169Shandong University Outstanding Young Scholars ProgramTaiShan Industrial Experts Program tscy20190612
6 · The paper itself

Abstract

Transposons, plasmids, bacteriophages, and other mobile genetic elements facilitate horizontal gene transfer in the gut microbiota, allowing some pathogenic bacteria to acquire antibiotic resistance genes (ARGs). Currently, the relationship between specific ARGs and specific transposons in the comprehensive infant gut microbiome has not been elucidated. In this study, ARGs and transposons were annotated from the Unified Human Gastrointestinal Genome (UHGG) and the Early-Life Gut Genomes (ELGG). Association rules mining was used to explore the association between specific ARGs and specific transposons in UHGG, and the robustness of the association rules was validated using the external database in ELGG. Our results suggested that ARGs and transposons were more likely to be relevant in infant gut microbiota compared to adult gut microbiota, and nine robust association rules were identified, among which

Indexed as

Anti-Bacterial AgentsEscherichia coliBacteriaDrug Resistance, MicrobialGenome, MicrobialHumansInfantAnti-Bacterial Agentsantibiotic resistance genesassociation rules mininghorizontal gene transferinfant gut microbiotatransposons

Identifiers

PMID38112433
PMCPMC10826358
OpenAlexW4389936436

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.