Evidence map›Paper›PMID 38112416›Full record

ArticlemSystems2024

Variations in the oral microbiome and metabolome of methamphetamine users.

Dawei Wang, Yu Feng, Min Yang, Haihui Sun, Qingchen Zhang, Rongrong Wang, Shuqing Tong, Rui Su, Yan Jin, Yunshan Wang and 3 more

Open access · goldAbstract read
In one paragraph

Article in mSystems, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. A Comprehensive 4-layeredCurrent pharmaceutical biotechnology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Dawei Wang *Department of Orthopedic, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Yu Feng *Department of Orthopedic, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.ORCID 0000-0002-1362-5048
Min YangDepartment of Immunology, Shandong Provincial Key Laboratory of Infection and Immunology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Haihui SunDepartment of Cardiology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Qingchen ZhangDepartment of Orthopedics, Central hospital affiliated to Shandong First Medical University, Jinan, Shandong, China.
Rongrong WangDepartment of Clinical Laboratory, Shandong Provincial Hospital, Shandong University, Jinan, Shandong, China.
Shuqing TongDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Rui SuDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Yan JinDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Yunshan WangDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Zhiming LuDepartment of Clinical Laboratory, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.ORCID 0000-0003-1228-5739
Lihui HanDepartment of Immunology, Shandong Provincial Key Laboratory of Infection and Immunology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.
Yundong SunDepartment of Microbiology, Key Laboratory for Experimental Teratology of Ministry of Education, School of Basic Medicine, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, China.ORCID 0000-0001-5260-2212
Shandong Provincial Hospital · CNShandong University · CNJinan Central Hospital · CN

Funding

Major innovation project of shandong province 2021GXGC011305MOST | National Natural Science Foundation of China (NSFC) 81972057MOST | National Natural Science Foundation of China (NSFC) 82172313
6 · The paper itself

Abstract

Drug addiction can seriously damage human physical and mental health, while detoxification is a long and difficult process. Although studies have reported changes in the oral microbiome of methamphetamine (METH) users, the role that the microbiome plays in the process of drug addiction is still unknown. This study aims to explore the function of the microbiome based on analysis of the variations in the oral microbiome and metabolome of METH users. We performed the 16S rRNA sequencing analysis based on the oral saliva samples collected from 278 METH users and 105 healthy controls (CTL). In addition, the untargeted metabolomic profiling was conducted based on 220 samples. Compared to the CTL group, alpha diversity was reduced in the group of METH users and the relative abundances of

Indexed as

Amphetamine-Related DisordersMethamphetamineMicrobiotaHumansMetabolomeRNA, Ribosomal, 16STryptaminesMethamphetamineRNA, Ribosomal, 16STryptamines16S rRNA sequencingdetoxificationmethamphetamine usersoral metabolitesoral microbiome

Identifiers

PMID38112416
PMCPMC10804968
OpenAlexW4389949127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.