Evidence map›Paper›PMID 38112139›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2023

[Role and mechanisms of CHI3L1 in coronary artery lesions in a mouse model of Kawasaki disease-like vasculitis].

Yue Cao, Shuai Gao, Gang Luo, Shui-Yan Zhao, Ya-Qi Tang, Zhan-Hui DU, Si-Lin Pan

Open access · greenAbstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Yue CaoHeart Center, Women and Children's Hospital, Qingdao University, Qingdao, Shandong 266034, China (Pan S-L, Email: silinpan@ 126. com).
Shuai GaoHeart Center, Women and Children's Hospital, Qingdao University, Qingdao, Shandong 266034, China (Pan S-L, Email: silinpan@ 126. com).
Gang LuoHeart Center, Women and Children's Hospital, Qingdao University, Qingdao, Shandong 266034, China (Pan S-L, Email: silinpan@ 126. com).
Shui-Yan ZhaoHeart Center, Women and Children's Hospital, Qingdao University, Qingdao, Shandong 266034, China (Pan S-L, Email: silinpan@ 126. com).
Ya-Qi TangHeart Center, Women and Children's Hospital, Qingdao University, Qingdao, Shandong 266034, China (Pan S-L, Email: silinpan@ 126. com).
Zhan-Hui DUHeart Center, Women and Children's Hospital, Qingdao University, Qingdao, Shandong 266034, China (Pan S-L, Email: silinpan@ 126. com).
Si-Lin PanHeart Center, Women and Children's Hospital, Qingdao University, Qingdao, Shandong 266034, China (Pan S-L, Email: silinpan@ 126. com).
Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the role and potential mechanisms of chitinase-3-like protein 1 (CHI3L1) in coronary artery lesions in a mouse model of Kawasaki disease (KD)-like vasculitis.

methodsFour-week-old male SPF-grade C57BL/6 mice were randomly divided into a control group and a model group, with 10 mice in each group. The model group mice were intraperitoneally injected with 0.5 mL of

resultsThe serum level of CHI3L1 in the model group was significantly higher than that in the control group (

conclusionsIn the LCWE-induced mouse model of KD-like vasculitis, the expression levels of CHI3L1 in serum and coronary arteries increase, and it may play a role in coronary artery lesions through endothelial cell apoptosis mediated by inflammatory reactions.

Indexed as

Mucocutaneous Lymph Node SyndromeAnimalsbcl-2-Associated X ProteinCadherinsCaspase 3Chitinase-3-Like Protein 1Coronary VesselsMaleMiceMice, Inbred C57BLNF-kappa Bvon Willebrand Factorbcl-2-Associated X ProteinCadherinsCaspase 3Chitinase-3-Like Protein 1NF-kappa Bvon Willebrand FactorApoptosisChitinase-3-like protein 1Coronary artery lesionKawasaki diseaseMouseVasculitis

Identifiers

PMID38112139
PMCPMC10731963
OpenAlexW4389958481

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.