Evidence map›Paper›PMID 38111945›Full record

ArticleInternational journal of ophthalmology2023

Retinal microvascular and microstructural alterations in the diagnosis of meibomian gland dysfunction in severely obese population: a new approach.

Hai Huang, Xiao-Yu Wang, Hong Wei, Min Kang, Jie Zou, Qian Ling, San-Hua Xu, Hui Huang, Xu Chen, Yi-Xin Wang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of ophthalmology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 71% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Hai HuangNanchang Aier Eye Hospital, Nanchang 330006, Jiangxi Province, China.
Xiao-Yu WangDepartment of Endocrinology and Metabolism, the First Affiliated Hospital of Nanchang University, Jiangxi Clinical Research Center for Endocrine and Metabolic Disease, Jiangxi Branch of National Clinical Research Center for Metabolic Disease, Nanchang 330006, Jiangxi Province, China.
Hong WeiDepartment of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200433, China.
Min KangDepartment of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200433, China.
Jie ZouDepartment of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200433, China.
Qian LingDepartment of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200433, China.
San-Hua XuDepartment of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200433, China.
Hui HuangDepartment of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200433, China.
Xu ChenDepartment of Ophthalmology and Visual Sciences, Maastricht University, Maastricht 6200MA, Limburg Province, Netherlands.
Yi-Xin WangSchool of Optometry and Vision Sciences, Cardiff University, Cardiff CF244HQ, United Kingdom.
Yi ShaoDepartment of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200433, China.
Yao YuDepartment of Endocrinology and Metabolism, the First Affiliated Hospital of Nanchang University, Jiangxi Clinical Research Center for Endocrine and Metabolic Disease, Jiangxi Branch of National Clinical Research Center for Metabolic Disease, Nanchang 330006, Jiangxi Province, China.
First Affiliated Hospital of Nanchang University · CNAnyang Eye Hospital · CNCardiff University · GBEye & ENT Hospital of Fudan University · CNMaastricht University · NLNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo study retinal microvascular and microstructural alterations in meibomian gland dysfunction (MGD) in severely obese population using optical coherence tomography angiography (OCTA).

methodsTwelve MGD patients with severely obese population (PAT group; 24 eyes) and 12 healthy controls (HC group; 24 eyes) were recruited. OCTA images were segmented into five [superior (S), nasal (N), inferior (I), temporal (T), and central foveal (C)] or nine [inner superior (IS), outer superior (OS), inner nasal (IN), outer nasal (ON), inner inferior (II), outer inferior (OI), inner temporal (IT), outer temporal (OT), and C] subregions. The superficial vessel density (SVD), retinal thickness (RT), foveal avascular zone (FAZ) parameters, and retinal volume were measured.

resultsVisual acuity was significantly different between two groups (0.8±0.17 in PAT group

conclusionVision may be affected in patients with MGD due to changes in retinal microvessels and microstructures. These changes detected by OCTA may be a potential marker for diagnosing MGD in severe obesity.

Indexed as

meibomian gland dysfunctionoptical coherence tomography angiographyretinal thicknessseverely obesitysuperficial vessel density

Identifiers

PMID38111945
PMCPMC10700072
OpenAlexW4388960079

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.