Evidence map›Paper›PMID 38111751›Full record

ArticleOpen forum infectious diseases2023

Serious Adverse Events and Laboratory Monitoring Regimens for Outpatient Parenteral Antimicrobial Therapy With Cefazolin and Ceftriaxone.

Shawnalyn W Sunagawa, Sarah Arduser, Molly M Miller, Elizabeth Lyden, Melissa LeMaster, Nicolas Cortes-Penfield, Richard J Hankins, Scott J Bergman, Bryan T Alexander

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shawnalyn W SunagawaDepartment of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, Nebraska, USA.
Sarah ArduserDepartment of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, Nebraska, USA.
Molly M MillerDepartment of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, Nebraska, USA.ORCID https://orcid.org/0009-0008-2768-2722
Elizabeth LydenCollege of Public Health, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Melissa LeMasterDepartment of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, Nebraska, USA.
Nicolas Cortes-PenfieldDivison of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Richard J HankinsDivison of Infectious Diseases, University of Nebraska Medical Center, Omaha, Nebraska, USA.
Scott J BergmanDepartment of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0002-6466-9518
Bryan T AlexanderDepartment of Pharmaceutical and Nutrition Care, Nebraska Medicine, Omaha, Nebraska, USA.ORCID https://orcid.org/0000-0001-7656-2569

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optimal laboratory monitoring frequency for outpatient parenteral antimicrobial therapy-related adverse events (OPAT-AEs) during cefazolin and ceftriaxone therapy is not well defined. We identified 2.7 OPAT-AEs per 1000 sets of weekly laboratory tests in this population, suggesting that less intensive laboratory monitoring may be safe and reasonable.

Indexed as

adverse eventscefazolinceftriaxonelaboratory techniques and proceduresoutpatient parenternal antimicrobial therapy

Identifiers

PMID38111751
PMCPMC10727193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.