Evidence map›Paper›PMID 38111705›Full record

ReviewFrontiers in endocrinology2023

Alterations in cellular metabolism under different grades of glioma staging identified based on a multi-omics analysis strategy.

Xianlei Yan, Jinwei Li, Yang Zhang, Cong Liang, Pengcheng Liang, Tao Li, Quan Liu, Xuhui Hui

Erratum issuedAbstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Xianlei Yan *Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Jinwei Li *Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yang Zhang *Department of Vascular Surgery, Fuwai Yunnan Cardiovascular Hospital, Affiliated Cardiovascular Hospital of Kunming Medical University, Kunming, Yunnan, China.
Cong LiangDepartment of Pharmacy, Liuzhou Workers Hospital, Liuzhou, Guangxi, China.
Pengcheng LiangDepartment of Neurosurgery, Liuzhou Workers Hospital, Liuzhou, Guangxi, China.
Tao LiDepartment of Medical Imaging, Liuzhou Workers Hospital, Liuzhou, Guangxi, China.
Quan LiuDepartment of Neurosurgery, Liuzhou Workers Hospital, Liuzhou, Guangxi, China.
Xuhui HuiDepartment of Neurosurgery, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glioma is a type of brain tumor closely related to abnormal cell metabolism. Firstly, multiple combinatorial sequencing studies have revealed this relationship. Genomic studies have identified gene mutations and gene expression disorders related to the development of gliomas, which affect cell metabolic pathways. In addition, transcriptome studies have revealed the genes and regulatory networks that regulate cell metabolism in glioma tissues. Metabonomics studies have shown that the metabolic pathway of glioma cells has changed, indicating their distinct energy and nutritional requirements. This paper focuses on the retrospective analysis of multiple groups combined with sequencing to analyze the changes in various metabolites during metabolism in patients with glioma. Finally, the changes in genes, regulatory networks, and metabolic pathways regulating cell metabolism in patients with glioma under different metabolic conditions were discussed. It is also proposed that multi-group metabolic analysis is expected to better understand the mechanism of abnormal metabolism of gliomas and provide more personalized methods and guidance for early diagnosis, treatment, and prognosis evaluation of gliomas.

Indexed as

Brain NeoplasmsGliomaHumansMultiomicsRetrospective StudiesTranscriptomebiomarkercellular metabolismgliomamulti-omics analysissingle-cell

Identifiers

PMID38111705
PMCPMC10726964

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.