ArticlePeerJ2023
Diagnostic value of albumin/fibrinogen ratio and C-reactive protein/albumin/globulin ratio for periprosthetic joint infection: a retrospective study.
Article in PeerJ, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 5 citations in OpenAlex.
- Common Serum Biomarkers and Combination Ratios in the Diagnosis of Periprosthetic Joint Infection Following Total Hip Arthroplasty.Microorganisms · 2026Article
- The diagnostic role of albumin-based ratio markers for periprosthetic joint infection.Frontiers in cellular and infection microbiology · 2026Article
- Predictive Value of the Serum CRP/Prealbumin Ratio for Sepsis in Pregnant and Postpartum Women.Journal of pregnancy · 2026Article
- Machine learning-based prediction of carbapenem-resistantFrontiers in pharmacology · 2026Article
- A nomogram prediction model for the risk of intra-abdominal infection after endoscopic full-thickness resection of gastric submucosal tumors.Biomedical engineering online · 2025Article
- Evaluation of the Diagnostic Accuracy of Serum Albumin and Globulin in Pyogenic Spondylitis.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The study aims to explore diagnostic value of albumin/fibrinogen ratio (AFR) and C-reactive protein (CRP)/albumin (ALB)/globulin (GLO) ratio (CAGR) for periprosthetic joint infection (PJI). Methods: A retrospective analysis was conducted on clinical data collected from 190 patients who had joint replacement surgery in Qilu Hospital of Shandong University (Qingdao), from January 2017 to December 2022. Based on the occurrence of PJI after surgery, patients were divided as an infection group (10 cases) and non-infection group (180 cases). Diagnostic indicators were analyzed, univariate and multivariate logistic regression analyses were further performed to identify factors related to PJI. Sensitivity and specificity of AFR and CAGR, both individually and in combination, were calculated using ROC curves, and their diagnostic performance was compared based on the area under the curve (AUC). Results: Levels of CRP, ESR, FIB, GLO, and CAGR were significantly higher in the infection group than in non-infection group ( Conclusion: Abnormal levels of AFR and CAGR are associated with PJI, and their combined use has certain diagnostic value for PJI.
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Registered trials
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