Evidence map›Paper›PMID 38111074›Full record

ReviewChinese medicine2023

Research progress on antitumor mechanisms and molecular targets of Inula sesquiterpene lactones.

Fei Cao, Chu Chu, Jiang-Jiang Qin, Xiaoqing Guan

Abstract readReview
In one paragraph

Review in Chinese medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Cytotoxic and Antimicrobial Activity of theMolecules (Basel, Switzerland) · 2025
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fei CaoCollege of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Chu ChuCollege of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Jiang-Jiang QinCollege of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, Zhejiang, China. jqin@ucas.ac.cn.
Xiaoqing GuanZhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, 310022, Zhejiang, China. guanxq1991@outlook.com.ORCID http://orcid.org/0000-0001-7887-8719

Funding

National Key R and D Program of China 2021YFA0910101Program of Zhejiang Provincial TCM Sci-tech Plan 2020ZZ005Traditional Chinese Medicine Science and Technology Program of Zhejiang Province 2023ZR003
6 · The paper itself

Abstract

The pharmacological effects of natural product therapy have received sigificant attention, among which terpenoids such as sesquiterpene lactones stand out due to their biological activity and pharmacological potential as anti-tumor drugs. Inula sesquiterpene lactones are a kind of sesquiterpene lactones extracted from Inula species. They have many pharmacological activities such as anti-inflammation, anti-asthma, anti-tumor, neuroprotective and anti-allergic. In recent years, more and more studies have proved that they are important candidate drugs for the treatment of a variety of cancers because of its good anti-tumor activity. In this paper, the structure, structure-activity relationship, antitumor activities, mechanisms and targets of Inula sesquiterpene lactones reported in recent years were reviewed in order to provide clues for the development of novel anticancer drugs.

Indexed as

AntitumorInula sesquiterpene lactonesMechanisms of actionMolecular targetStructure–activity relationship

Identifiers

PMID38111074
PMCPMC10726648

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.