Evidence map›Paper›PMID 38110971›Full record

ArticleRadiation oncology (London, England)2023

Outcomes of carbon ion radiotherapy compared with segmentectomy for ground glass opacity-dominant early-stage lung cancer.

Teruaki Mizobuchi, Akihiro Nomoto, Hironobu Wada, Naoyoshi Yamamoto, Mio Nakajima, Takehiko Fujisawa, Hidemi Suzuki, Ichiro Yoshino

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiation oncology (London, England), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Teruaki MizobuchiDepartment of General Thoracic Surgery, Social Welfare Organization Saiseikai Imperial Gift Foundation, Chibaken Saiseikai Narashino Hospital, 1-8-1 Izumi-Cho, Narashino-Shi, Chiba, 275-8580, Japan. tmizobuc@gmail.com.
Akihiro NomotoDepartment of Radiology, Teikyo University School of Medicine, Tokyo, Japan.
Hironobu WadaDepartment of Pulmonary Surgery, International University of Health and Welfare Narita Hospital, Chiba, Japan.
Naoyoshi YamamotoDepartment of Internal Medicine, Chosei Municipal Hospital, Chiba, Japan.
Mio NakajimaNational Institutes for Quantum Science and Technology QST Hospital, Chiba, Japan.
Takehiko FujisawaChiba Foundation for Health Promotion and Disease Prevention, Chiba, Japan.
Hidemi SuzukiDepartments of General Thoracic Surgery, Departments of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Ichiro YoshinoDepartments of General Thoracic Surgery, Departments of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Chiba University · JPChibaken Saiseikai Narashino Hospital · JPInternational University of Health and Welfare · JPNational Institutes for Quantum Science and Technology · JPTeikyo University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to compare the outcomes of patients with ground-grass opacity (GGO)-dominant non-small cell lung cancer (NSCLC) who were treated with carbon ion radiotherapy (CIRT) versus segmentectomy.

methodsA retrospective review of medical records was conducted. The study included 123 cases of clinical stage 0/IA peripheral NSCLC treated with single-fraction CIRT from 2003 to 2012, 14 of which were determined to be GGO-dominant and were assigned to CIRT group. As a control, 48 consecutive patients who underwent segmentectomy for peripheral GGO-dominant clinical stage IA NSCLC were assigned to segmentectomy group.

resultsThe patients in CIRT group, compared with segmentectomy group, were significantly older (75 ± 7.2 vs. 65 ± 8.2 years, P = 0.000660), more likely to be male (13/14 vs. 22/48, P = 0.00179), and had a lower forced vital capacity (91 ± 19% vs. 110 ± 13%, P = 0.0173). There was a significant difference in the 5-years overall survival rate (86% vs. 96%, P = 0.000860), but not in the 5-years disease-specific survival rate (93% vs. 98%, P = 0.368). DISCUSSION: Compared with segmentectomy, CIRT may be an alternative option for patients with early GGO-dominant NSCLC who are poor candidates for, or who refuse, surgery.

Indexed as

Carcinoma, Non-Small-Cell LungHeavy Ion RadiotherapyLung NeoplasmsFemaleHumansLungMaleNeoplasm StagingPneumonectomyRetrospective StudiesCarbon ion radiotherapyGround glass opacityLung cancerSegmentectomy

Identifiers

PMID38110971
PMCPMC10726495
OpenAlexW4389880776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.