Evidence map›Paper›PMID 38110887›Full record

ArticleBMC public health2023

Application of the 'online assessment + FOBT at home' to improve participation and the efficacy of opportunistic screening for colorectal cancer: a retrospective cohort study.

Xudong Peng, Gang Tang, Yonghong Wang, Fanling Zeng, Yuedong Chen, Weidan Zhang, Chunmei Mo, Yana Yang, Shuang Li, Lian Bai and 12 more

Abstract read
In one paragraph

Article in BMC public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Xudong Peng *Gastrointestinal Surgical Unit, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China.
Gang Tang *Gastrointestinal Surgical Unit, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China.
Yonghong WangHealth Management Center, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China.
Fanling ZengHealth Management Center, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China.
Yuedong ChenDepartment of Gastrointestinal Surgery, People's Hospital of Tongliang District, Chongqing, China.
Weidan ZhangDepartment of Gastrointestinal Surgery, People's Hospital of Tongliang District, Chongqing, China.
Chunmei MoHealth Management Center, People's Hospital of Tongliang District, Chongqing, China.
Yana YangHealth Management Center, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China.
Shuang LiGastrointestinal Surgical Unit, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China.
Lian BaiGastrointestinal surgery Unit, Yongchuan hospital of Chongqing Medical university, Chongqing, China.
Dachun XiaoGastrointestinal surgery Unit, Yongchuan hospital of Chongqing Medical university, Chongqing, China.
Guolian ZhengHealth Management Department, Yongchuan Hospital of Chongqing Medical University, Chongqing, China.
Wenhua RanDepartment of General Surgery, Qianjiang Central Hospital, Chongqing, Chongqing, China.
Cheng ChenDepartment of General Surgery, Qianjiang Central Hospital, Chongqing, Chongqing, China.
Yonghong YangDepartment of Health Management, Qianjiang Central Hospital, Chongqing, Chongqing, China.
Yuanze GaoAnorectal Department, The Ninth People's Hospital of Chongqing, Chongqing, China.
Shuangwei ZhuGastroenteroanal Surgery, Fuling People's Hospital Of Chongqing, Chongqing, China.
Zheng HuangGastrointestinal Surgical Unit, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China.
Dongqing ZhaoGastrointestinal Surgical Unit, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China.
Chaofeng WuGastrointestinal Surgical Unit, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China.
Li XuHealth Management Center, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China. 451112099@qq.com.
Zhengqiang WeiGastrointestinal Surgical Unit, The First Affiliated Hospital of Chongqing Medical University, No. 1, Youyi Road, Yuzhong District, 400000, Chongqing, China. 1980900547@qq.com.

Funding

Chongqing key diseases Research and Application Demonstration Program from Chongqing Municipal Health Commission (Colorectal Cancer prevention and Treatment Technology Research and Application Demonstration [No. 2019ZX003]) No. 2019ZX003
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) screening faces two major challenges: insufficient screening coverage and poor adherence. A smartphone applet named "Early Screening Assistant (ESA)" was developed to create an online risk-assessment and fecal occult blood test (FOBT) at home. This retrospective study was designed to evaluate whether the new CRC screening strategy can improve the colonoscopy participation rate (PR) and lesion detection rate (DR).

methodsIn total, 6194 individuals who accepted normal health examinations and CRC screening based on the ESA from June 2020 to May 2022 were assigned to the ESA group. Accordingly, 7923 inhabitants who only accepted normal health examinations were assigned to the control group. The colonoscopy PR and neoplastic lesion DR were then compared between the two groups.

resultsOverall, a higher proportion of subjects in the ESA group (285 of 6194 [4.6%]) completed colonoscopy than in the control group (126 of 7923, [1.6%]), p < 0.01). The neoplastic lesion DR also significantly increased in the ESA group (76 of 6194 [1.22%]) compared with the control group (15 of 7923 [0.19%]) (p < 0.01). The adjusted diagnostic sensitivity and specificity of the "Online assessment + FOBT at home" were 41.5% and 62.6% for neoplastic lesions, respectively.

conclusionsThis retrospective cohort study confirmed that the new CRC screening strategy based on the "Online assessment + FOBT at home" can improve colonoscopy participation and the neoplastic lesion detection rate and may represent a promising screening strategy for CRC.

trial registrationThis study was registered in China Clinical Trial Registry ( https://www.chictr.org.cn ) on 29/09/2022. REGISTRATION NUMBER: ChiCTR2200064186.

Indexed as

Colorectal NeoplasmsOccult BloodColonoscopyEarly Detection of CancerHumansMass ScreeningRetrospective StudiesColonoscopyColorectal cancer (CRC)Fecal occult blood test (FOBT)MediaOpportunistic screeningSocial

Identifiers

PMID38110887
PMCPMC10729553

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.