Evidence map›Paper›PMID 38110791›Full record

ArticleMolecular imaging and biology2024

Detection of Intestinal Inflammation by Vascular Adhesion Protein-1-Targeted [

Achol A Bhowmik, Taina R H Heikkilä, Lauri Polari, Jenni Virta, Heidi Liljenbäck, Olli Moisio, Xiang-Guo Li, Riikka Viitanen, Sirpa Jalkanen, Jukka Koffert and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular imaging and biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Article
  3. Combined [European journal of nuclear medicine and molecular imaging · 2026
    Observational
  4. A NovelPharmaceutics · 2025
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Achol A BhowmikTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland.ORCID 0000-0002-1491-5899
Taina R H HeikkiläCell Biology, Biosciences, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland.
Lauri PolariCell Biology, Biosciences, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland.ORCID 0000-0002-0052-6489
Jenni VirtaTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland.ORCID 0000-0003-1062-8187
Heidi LiljenbäckTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland.ORCID 0000-0001-9372-1584
Olli MoisioTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland.ORCID 0000-0002-2473-459X
Xiang-Guo LiTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland.ORCID 0000-0002-9118-7223
Riikka ViitanenTurku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland.ORCID 0000-0003-0937-356X
Sirpa JalkanenInFLAMES Research Flagship, University of Turku, Turku, Finland.ORCID 0000-0002-1922-9732
Jukka Koffert *Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland.ORCID 0000-0003-3375-8961
Diana M Toivola *Cell Biology, Biosciences, Faculty of Science and Engineering, Åbo Akademi University, Turku, Finland.ORCID 0000-0001-7165-9839
Anne Roivainen *Turku PET Centre, University of Turku, Kiinamyllynkatu 4-8, FI-20520, Turku, Finland. anne.roivainen@utu.fi.ORCID 0000-0002-4006-7977
University of Turku · FIÅbo Akademi University · FI

Funding

Terveyden Tutkimuksen Toimikunta 315139Terveyden Tutkimuksen Toimikunta 332582Terveyden Tutkimuksen Toimikunta 347251Terveyden Tutkimuksen Toimikunta 350117Turun Yliopistollinen Keskussairaala ERVA 13856
6 · The paper itself

Abstract

purposeInflammatory bowel disease (IBD) can be imaged with positron emission tomography (PET), but existing PET radiopharmaceuticals have limited diagnostic accuracy. Vascular adhesion protein-1 (VAP-1) is an endothelial cell surface molecule that controls leukocyte extravasation into sites of inflammation. However, the role of inflammation-induced VAP-1 expression in IBD is still unclear. Therefore, this study investigated the utility of VAP-1-targeted [ PROCEDURES: Studies were performed using K8

resultsIntestinal inflammation could be visualized by [

conclusionsThis study suggests that the VAP-1-targeting [

Indexed as

Heterocyclic Compounds, 1-RingInflammatory Bowel DiseasesPositron Emission Tomography Computed TomographyAnimalsDisease Models, AnimalGallium RadioisotopesHumansInflammationMicePositron-Emission TomographySialic Acid Binding Immunoglobulin-like Lectins1,4,7,10-tetraazacyclododecane- 1,4,7,10-tetraacetic acidGallium RadioisotopesHeterocyclic Compounds, 1-RingSialic Acid Binding Immunoglobulin-like Lectins[68Ga]Ga-DOTA-Siglec-9Inflammatory bowel diseaseMurine colitisPositron emission tomographySiglec-9Vascular adhesion protein-1

Identifiers

PMID38110791
PMCPMC10973022
OpenAlexW4389886732

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.