Evidence map›Paper›PMID 38110627›Full record

ArticleEuropean radiology2024

The earliest optimal timing for total-body

Zhe Zheng, Huaping Gao, Yu Lin, Haojun Yu, Wujian Mao, Runjun Yang, Yibo He, Xueqi Chen, Ha Wu, Pengcheng Hu and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Impaired glymphatic function is associated with synaptic loss in cognitive impairment.European journal of nuclear medicine and molecular imaging · 2026
    Article
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  3. Exploration the feasibility and additional value of [European journal of nuclear medicine and molecular imaging · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zhe ZhengDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Huaping GaoDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Yu LinDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Haojun YuDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Wujian MaoDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Runjun YangDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Yibo HeDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Xueqi ChenDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Ha WuDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China.
Pengcheng HuDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China. hu.pengcheng@zs-hospital.sh.cn.
Hongcheng ShiDepartment of Nuclear Medicine, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai, 200032, China. shi.hongcheng@zs-hospital.sh.cn.ORCID http://orcid.org/0000-0003-4813-4262

Funding

Clinical Research Plan of SHDC No. SHDC2020CR3079BShanghai Municipal Commission of Economy and Informatization 201901014Shanghai Municipal Key Clinical Specialty shslczdzk03401
6 · The paper itself

Abstract

objectivesTo investigate the earliest optimal timing for positron emission tomography (PET) scans after

methodsThis prospective study enrolled patients who underwent 60-min dynamic

resultsA total of 30 patients with suspected malignant tumours were analysed. In the images reconstructed over 10-min intervals, longer acquisition times were associated with lower background uptake and better image quality. Some lesions could not be detected until G30-40. The lesion detection rate, uptake, and LBRs did not differ significantly among G30-40, G40-50, and G50-60 (all p > 0.05). The SUVmean and LBRs of primary tumours in the reconstructed images did not differ significantly among the 5-min intervals between 30 and 40 min; for metastatic and benign lesions, G34-39 and G35-40 showed significantly better SUVmean and LBR values than the other images. The G34-39 and G50-60 scans showed no significant differences in uptake, LBRs, or detection rates (all p > 0.05).

conclusionThe earliest optimal time to start acquisition was 34 min after injection of half-dose [ CLINICAL RELEVANCE STATEMENT: This study evaluated KEY POINTS: • A prospective single-centre study showed that the earliest optimal time point to start acquisition was 34 min after injection of half-dose [

Indexed as

Gallium RadioisotopesPositron Emission Tomography Computed TomographyRadiopharmaceuticalsAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeoplasmsProspective StudiesQuinolinesSignal-To-Noise RatioTime FactorsWhole Body Imaging68Ga-FAPIGallium RadioisotopesQuinolinesRadiopharmaceuticals68Ga-fibroblast activation protein inhibitorPositron emission tomographyTissue distribution

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.