Evidence map›Paper›PMID 38110614›Full record

ArticleCommunications biology2023

Tumor microenvironment remodeling plus immunotherapy could be used in mesenchymal-like tumor with high tumor residual and drug resistant rate.

Shuai Shen, Xing Liu, Qing Guo, Qingyu Liang, Jianqi Wu, Gefei Guan, Cunyi Zou, Chen Zhu, Zihao Yan, Tianqi Liu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Shuai Shen *Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.ORCID 0000-0001-9031-3200
Xing Liu *Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Qing Guo *Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Qingyu LiangDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Jianqi WuDepartment of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Gefei GuanDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Cunyi ZouDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Chen ZhuDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Zihao YanDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, Liaoning, China.
Tianqi LiuDepartment of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Ling ChenDepartment of Neurosurgery, Chinese People's Liberation Army of China (PLA) General Hospital, Medical School of Chinese PLA, Institute of Neurosurgery of Chinese PLA, Beijing, China.
Peng ChengDepartment of Neurosurgery, The First Hospital of China Medical University, Shenyang, Liaoning, China. chengpengcmu@cmu.edu.cn.ORCID 0009-0007-8059-6850
Wen ChengDepartment of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. cmu071207@163.com.ORCID 0000-0003-0689-1695
Anhua WuDepartment of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China. ahwu@cmu.edu.cn.ORCID 0000-0002-3402-1884
China Medical University · CNFirst Hospital of China Medical University · CNChinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epithelial-mesenchymal transition (EMT) is a common process during tumor progression and is always related to residual tumor, drug resistance and immune suppression. However, considering the heterogeneity in EMT process, there is still a need to establish robust EMT classification system with reasonable molecular, biological and clinical implications to investigate whether these unfavorable survival factors are common or unique in different individuals. In our work, we classify tumors with four EMT status, that is, EMT

Indexed as

NeoplasmsSignal TransductionEpithelial-Mesenchymal TransitionHumansImmunotherapyProto-Oncogene Proteins c-aktTumor MicroenvironmentProto-Oncogene Proteins c-akt

Identifiers

PMID38110614
PMCPMC10728080
OpenAlexW4389887682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.