Evidence map›Paper›PMID 38110564›Full record

ArticleThe Journal of antibiotics2024

Talcarpones A and B: bisnaphthazarin-derived metabolites from the Australian fungus Talaromyces johnpittii sp. nov. MST-FP2594.

Alastair E Lacey, Scott A Minns, Rachel Chen, Daniel Vuong, Ernest Lacey, John A Kalaitzis, Yu Pei Tan, Roger G Shivas, Mark S Butler, Andrew M Piggott

Abstract read
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Article in The Journal of antibiotics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Seven New Series and Four New Species in SectionsJournal of fungi (Basel, Switzerland) · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alastair E LaceyMicrobial Screening Technologies, Smithfield, NSW, 2164, Australia.
Scott A MinnsMicrobial Screening Technologies, Smithfield, NSW, 2164, Australia.
Rachel ChenMicrobial Screening Technologies, Smithfield, NSW, 2164, Australia.
Daniel VuongMicrobial Screening Technologies, Smithfield, NSW, 2164, Australia.
Ernest LaceyMicrobial Screening Technologies, Smithfield, NSW, 2164, Australia.ORCID 0000-0002-5387-2721
John A KalaitzisSchool of Natural Sciences, Macquarie University, Macquarie Park, NSW, 2109, Australia.
Yu Pei TanQueensland Plant Pathology Herbarium, Department of Agriculture and Fisheries, Brisbane, QLD, 4102, Australia.
Roger G ShivasQueensland Plant Pathology Herbarium, Department of Agriculture and Fisheries, Brisbane, QLD, 4102, Australia.
Mark S ButlerMSBChem Consulting, New Farm, QLD, 4005, Australia.
Andrew M PiggottSchool of Natural Sciences, Macquarie University, Macquarie Park, NSW, 2109, Australia. andrew.piggott@mq.edu.au.ORCID 0000-0002-5308-5314

Funding

Department of Industry, Innovation and Science, Australian Government (Department of Industry, Innovation and Science) CRCPFIVE000119
6 · The paper itself

Abstract

Talcarpones A (1) and B (2) are rare bisnaphthazarin derivatives produced by Talaromyces johnpittii (ex-type strain MST-FP2594), a newly discovered Australian fungus, which is formally described and named herein. The talcarpones were isolated along with the previously reported monomeric naphthoquinone, aureoquinone (3), suggesting a biosynthetic link between these metabolites. Talcarpone A is a lower homologue of hybocarpone (4), which was first isolated from a mycobiont of the lichen Lecanora hybocarpa. The structures of 1 and 2 were elucidated by detailed spectroscopic analysis, molecular modelling and comparison with literature data. Talcarpones 1 and 2 exhibited moderate antifungal activity (MIC 0.78-3.1 µg ml

Indexed as

TalaromycesAntifungal AgentsAustraliaMolecular StructureAntifungal Agents

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.