Evidence map›Paper›PMID 38110546›Full record

ReviewNature reviews. Gastroenterology & hepatology2024

Guidelines for best practices in monitoring established coeliac disease in adult patients.

Luca Elli, Daniel Leffler, Christophe Cellier, Benjamin Lebwohl, Carolina Ciacci, Michael Schumann, Knut E A Lundin, Stefania Chetcuti Zammit, Reena Sidhu, Leda Roncoroni and 18 more

Open access · bronzeAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 2 pooled it
20.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 75 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Observational
  11. IgA Subclasses and Free Light Chains in Celiac Disease: A Pilot Study.International journal of molecular sciences · 2026
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 18 institutions in 10 countries.

Luca ElliCenter for Prevention and Diagnosis of Celiac Disease-Gastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Luca.elli@policlinico.mi.it.
Daniel LefflerCeliac Center, Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School, Boston, MA, USA.
Christophe CellierDepartment of Gastroenterology and Endoscopy, CELAC network, AP-HP Centre, Hôpital Européen Georges Pompidou, Université de Paris, Cité and Institut National du Cancer, Paris, France.
Benjamin LebwohlCeliac Disease Center, Department of Medicine, Columbia University Irving Medical Center, Columbia University, New York, NY, USA.
Carolina CiacciCenter for Celiac Disease, Gastrointestinal Unit, AOU San Giovanni di Dio e Ruggi D'Aragona and Department of Medicine Surgery Dentistry, Scuola Medica Salernitana, University of Salerno, Salerno, Italy.ORCID http://orcid.org/0000-0002-7426-1145
Michael SchumannCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Berlin, Germany.
Knut E A LundinK.G. Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway.ORCID http://orcid.org/0000-0003-1713-5545
Stefania Chetcuti ZammitDepartment of Medicine, Division of Gastroenterology, Mater Dei Hospital, Msida, Malta.
Reena SidhuDepartment of Infection, Immunity and Cardiovascular Diseases, Royal Hallamshire Hospital, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0003-0820-2400
Leda RoncoroniCenter for Prevention and Diagnosis of Celiac Disease-Gastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Julio C BaiDepartment of Medicine, Dr. C. Bonorino Udaondo Gastroenterology Hospital, Buenos Aires, Argentina.
Anne R LeeCeliac Disease Center, Department of Medicine, Columbia University Irving Medical Center, Columbia University, New York, NY, USA.
Melinda DennisCeliac Center, Beth Israel Deaconess Medical Center (BIDMC), Harvard Medical School, Boston, MA, USA.
Marie E RobertDepartment of Pathology and Medicine, Yale University School of Medicine, New Haven, CT, USA.
Kamran RostamiDepartment of Gastroenterology, Palmerston North District Health Board (DHB), Palmerston North, New Zealand.
Sherine KhaterDepartment of Gastroenterology and Endoscopy, CELAC network, AP-HP Centre, Hôpital Européen Georges Pompidou, Université de Paris, Cité and Institut National du Cancer, Paris, France.
Isabel CominoDepartment of Microbiology and Parasitology, Faculty of Pharmacy, University of Seville, Seville, Spain.
Angel CebollaBiomedal S.L., Seville, Spain.ORCID http://orcid.org/0000-0002-6976-4522
Federica BranchiCharité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Medizinische Klinik für Gastroenterologie, Infektiologie und Rheumatologie, Berlin, Germany.
Elena F VerduDepartment of Medicine, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada.ORCID http://orcid.org/0000-0001-6346-2665
Juan Pablo StefanoloDepartment of Medicine, Dr. C. Bonorino Udaondo Gastroenterology Hospital, Buenos Aires, Argentina.
Randi WolfProgram in Nutrition, Department of Health Studies & Applied Educational Psychology, Teachers College, Columbia University, New York, NY, USA.
Sheba Bergman-GoldenProgram in Nutrition, Department of Health Studies & Applied Educational Psychology, Teachers College, Columbia University, New York, NY, USA.
Nick TrottDepartment of Infection, Immunity and Cardiovascular Diseases, Royal Hallamshire Hospital, University of Sheffield, Sheffield, UK.
Luigia ScudellerIRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.ORCID http://orcid.org/0000-0001-7240-9567
Fabiana ZingoneDepartment of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0003-1133-1502
Lucia ScaramellaCenter for Prevention and Diagnosis of Celiac Disease-Gastroenterology and Endoscopy Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
David S SandersDepartment of Infection, Immunity and Cardiovascular Diseases, Royal Hallamshire Hospital, University of Sheffield, Sheffield, UK.
Royal Hallamshire Hospital · GBAssistance Publique – Hôpitaux de Paris · FRBeth Israel Deaconess Medical Center · USColumbia University · USColumbia University Irving Medical Center · USFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITHumboldt-Universität zu Berlin · DEAzienda USL di Bologna · ITBiomedal (Spain) · ESMater Dei Hospital · MTOslo University Hospital · NOPalmerston North Hospital · NZPopulation Health Research Institute · CAUniversidad de Sevilla · ESUniversity of Milan · ITUniversity of Padua · ITUniversity of Salerno · ITYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coeliac disease (CeD) is an immunological disease triggered by the consumption of gluten contained in food in individuals with a genetic predisposition. Diagnosis is based on the presence of small bowel mucosal atrophy and circulating autoantibodies (anti-type 2 transglutaminase antibodies). After diagnosis, patients follow a strict, life-long gluten-free diet. Although the criteria for diagnosis of this disease are well defined, the monitoring phase has been studied less and there is a lack of specific guidelines for this phase. To develop a set of clinical guidelines for CeD monitoring, we followed the Grading of Recommendations Assessment, Development and Evaluation methodology. Statements and recommendations with the level of evidence were developed and approved by the working group, which comprised gastroenterologists, pathologists, dieticians and biostatisticians. The proposed guidelines, endorsed by the North American and European coeliac disease scientific societies, make recommendations for best practices in monitoring patients with CeD based on the available evidence. The evidence level is low for many topics, suggesting that further research in specific aspects of CeD would be valuable. In conclusion, the present guidelines support clinicians in improving CeD treatment and follow-up and highlight novel issues that should be considered in future studies.

Indexed as

Celiac DiseaseGastroenterologistsAdultAutoantibodiesDiet, Gluten-FreeGenetic Predisposition to DiseaseHumansAutoantibodies

Identifiers

PMID38110546
OpenAlexW4389917498

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.