Evidence map›Paper›PMID 38110537›Full record

ArticleArchives of osteoporosis2023

The impact of a Fracture Liaison Service after 3 years on secondary fracture prevention and mortality in a Portuguese tertiary center.

Susana P Silva, Carolina Mazeda, Paulo Vilas-Boas, Maria do Céu Portelada, Gisela Eugénio, Anabela Barcelos

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of osteoporosis, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Introduction of an order set after hip fracture improves osteoporosis medication initiation and persistence: a population-based before-after analysis.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Susana P SilvaRheumatology Department, Centro Hospitalar Do Baixo Vouga, Av. Artur Ravara, 3814-501, Aveiro, Portugal. susanna_ps@hotmail.com.ORCID http://orcid.org/0000-0003-4797-047X
Carolina MazedaRheumatology Department, Centro Hospitalar Do Baixo Vouga, Av. Artur Ravara, 3814-501, Aveiro, Portugal.ORCID http://orcid.org/0000-0002-9200-5022
Paulo Vilas-BoasRheumatology Department, Centro Hospitalar Do Baixo Vouga, Av. Artur Ravara, 3814-501, Aveiro, Portugal.
Maria do Céu PorteladaRheumatology Department, Centro Hospitalar Do Baixo Vouga, Av. Artur Ravara, 3814-501, Aveiro, Portugal.
Gisela EugénioRheumatology Department, Centro Hospitalar Do Baixo Vouga, Av. Artur Ravara, 3814-501, Aveiro, Portugal.ORCID http://orcid.org/0000-0002-9366-322X
Anabela BarcelosRheumatology Department, Centro Hospitalar Do Baixo Vouga, Av. Artur Ravara, 3814-501, Aveiro, Portugal.ORCID http://orcid.org/0000-0002-4116-8964
Centro Hospitalar do Baixo Vouga · PTHospital de Egas Moniz · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the establishment of Fracture Liaison Services (FLS) worldwide, no study has evaluated their impact on the Portuguese population. Our work has shown that the implementation of an FLS is associated with a significant increase in OP treatment and a lower risk of secondary fracture. PURPOSE: Fracture Liaison Services (FLS) have been established worldwide, with positive effects on treatment, secondary fracture, mortality, and economic burden. However, no study has evaluated their impact on the Portuguese population. Therefore, we purposed to evaluate the effect of an FLS model in a Portuguese center on osteoporosis (OP) treatment, secondary fracture, and mortality rates, 3 years after a fragility fracture.

methodsPatients over 50 years old, admitted with a fragility fracture, between January 2017 and December 2020, were included in this retrospective study. Patients evaluated after FLS implementation (2019-2020) were compared with those evaluated before (2017-2018) and followed for 36 months. Predictors of secondary fracture and mortality were assessed using a multivariate Cox regression model, adjusted to potential confounders.

resultsA total of 551 patients were included (346 before and 205 after FLS). The FLS significantly increased the rate of OP treatment, when compared with standard clinical practice (8.1% vs 77.6%). During follow-up, the secondary fracture rate was 14.7% and 7.3%, before and after FLS, respectively. FLS was associated with a lower risk of secondary fracture (HR 0.39, C.I. 0.16-0.92). Although we observed a lower mortality rate (25.1% vs 13.7%), FLS was not a significant predictor of survival.

conclusionImplementing the FLS model in a Portuguese center has increased OP treatment and reduced the risk of secondary fracture. We believe that our work supports adopting FLS models in national programs.

Indexed as

Bone Density Conservation AgentsOsteoporosisOsteoporotic FracturesHumansMiddle AgedPortugalRetrospective StudiesSecondary PreventionBone Density Conservation AgentsFracture Liaison ServiceFragility fractureOsteoporosisSecondary prevention

Identifiers

PMID38110537
OpenAlexW4389888674

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.