Evidence map›Paper›PMID 38109676›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2023

Impact of COVID-19 on incidence and outcomes of post-infarction mechanical complications in Europe.

Daniele Ronco, Matteo Matteucci, Justine Mafalda Ravaux, Mariusz Kowalewski, Giulio Massimi, Federica Torchio, Cinzia Trumello, Shiho Naito, Nikolaos Bonaros, Michele De Bonis and 28 more

Open access · diamondAbstract read
In one paragraph

Article in Interdisciplinary cardiovascular and thoracic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

38 authors at 15 institutions in 6 countries.

Daniele RoncoDepartment of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, Netherlands.ORCID 0000-0001-5250-1796
Matteo MatteucciDepartment of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, Netherlands.ORCID 0000-0003-0694-2747
Justine Mafalda RavauxDepartment of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, Netherlands.
Mariusz KowalewskiDepartment of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, Netherlands.
Giulio MassimiDepartment of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, Netherlands.
Federica TorchioDepartment of Medicine and Surgery, Circolo Hospital, University of Insubria, Varese, Italy.
Cinzia TrumelloCardiothoracic Surgery Department, San Raffaele University Hospital, Milan, Italy.
Shiho NaitoDepartment of Cardiovascular Surgery, University Heart & Vascular Center Hamburg, Hamburg, Germany.
Nikolaos BonarosDepartment of Cardiac Surgery, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0002-7656-5812
Michele De BonisCardiothoracic Surgery Department, San Raffaele University Hospital, Milan, Italy.ORCID 0000-0001-9329-7437
Dario FinaDepartment of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, Netherlands.
Adam KowalówkaThoracic Research Centre, Collegium Medicum Nicolaus Copernicus University, Innovative Medical Forum, Bydgoszcz, Poland.ORCID 0000-0002-8239-9099
Marek DejaDepartment of Cardiac Surgery, Medical University of Silesia, School of Medicine in Katowice, Katowice, Poland.
Federica JiritanoDepartment of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, Netherlands.ORCID 0000-0002-6889-5686
Giuseppe Filiberto SerrainoDepartment of Experimental and Clinical Medicine, "Magna Graecia" University of Catanzaro, Catanzaro, Italy.
Jurij Matija KalisnikDepartment of Cardiac Surgery, Cardiovascular Center, Klinikum Nürnberg, Paracelsus Medical University, Nuremberg, Germany.
Carlo De VincentiisCardiac Surgery Unit, IRCCS Policlinico San Donato, San Donato Milanese, Italy.ORCID 0000-0002-9945-0057
Marco RanucciDepartment of Cardiovascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, San Donato Milanese, Italy.ORCID 0000-0002-4915-3572
Theodor FischleinDepartment of Cardiac Surgery, Cardiovascular Center, Klinikum Nürnberg, Paracelsus Medical University, Nuremberg, Germany.ORCID 0000-0001-9781-3590
Claudio Francesco RussoCardiac Surgery Unit, Cardio-Thoraco-Vascular Department, Niguarda Hospital, Milan, Italy.
Massimiliano CarrozziniCardiac Surgery Unit, Cardio-Thoraco-Vascular Department, Niguarda Hospital, Milan, Italy.ORCID 0000-0001-5506-0201
Udo BoekenDepartment of Cardiovascular Surgery, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.
Nikolaos KalampokasDepartment of Cardiovascular Surgery, University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany.
Michele GolinoDepartment of Medicine and Surgery, Circolo Hospital, University of Insubria, Varese, Italy.
Roberto De PontiDepartment of Medicine and Surgery, Circolo Hospital, University of Insubria, Varese, Italy.
Matteo PozziDepartment of Cardiac Surgery, Louis Pradel Cardiologic Hospital, Lyon, France.
Jean-François ObadiaDepartment of Cardiac Surgery, Louis Pradel Cardiologic Hospital, Lyon, France.
Matthias ThielmannDepartment of Thoracic and Cardiovascular Surgery, West-German Heart Center, University of Duisburg-Essen, Essen, Germany.ORCID 0000-0002-1007-2871
Roberto ScrofaniCardiac Surgery Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Stefania BlasiCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy.
Giovanni TroiseCardiac Surgery Unit, Poliambulanza Foundation Hospital, Brescia, Italy.
Carlo AntonaCardiac Surgery Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
Andrea De MartinoSection of Cardiac Surgery, University Hospital, Pisa, Italy.ORCID 0000-0003-2889-4918
Giosuè FalcettaSection of Cardiac Surgery, University Hospital, Pisa, Italy.
Guglielmo Actis DatoCardiac Surgery Department, Mauriziano Hospital, Turin, Italy.
Paolo SevergniniDepartment of Biotechnology and Sciences of Life, Circolo Hospital, University of Insubria, Varese, Italy.
Andrea MusazziCardiac Surgery Unit, Circolo Hospital, Varese, Italy.
Roberto LorussoDepartment of Cardiothoracic Surgery, Heart and Vascular Centre, Maastricht University Medical Centre, Maastricht, Netherlands.ORCID 0000-0002-1777-2045
Maastricht University Medical Centre · NLUniversity of Insubria · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITDüsseldorf University Hospital · DEFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITFondazione Poliambulanza Istituto Ospedaliero · ITHôpital Louis Pradel · FRIRCCS Policlinico San Donato · ITMedical University of Silesia · PLNuremberg Hospital · DESan Raffaele University of Rome · ITA. O. Ordine Mauriziano di Torino · ITInnsbruck Medical University · ATMagna Graecia University · ITWest German Heart and Vascular Center Essen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPost-acute myocardial infarction mechanical complications (post-AMI MCs) represent rare but life-threatening conditions, including free-wall rupture, ventricular septal rupture and papillary muscle rupture. During the coronavirus disease-19 (COVID-19) pandemic, an overwhelming pressure on healthcare systems led to delayed and potentially suboptimal treatments for time-dependent conditions. As AMI-related hospitalizations decreased, limited information is available whether higher rates of post-AMI MCs and related deaths occurred in this setting. This study was aimed to assess how COVID-19 in Europe has impacted the incidence, treatment and outcome of MCs.

methodsThe CAUTION-COVID19 study is a multicentre retrospective study collecting 175 patients with post-AMI MCs in 18 centres from 6 European countries, aimed to compare the incidence of such events, related patients' characteristics, and outcomes, between the first year of pandemic and the 2 previous years.

resultsA non-significant increase in MCs was observed [odds ratio (OR) = 1.15, 95% confidence interval (CI) 0.85-1.57; P = 0.364], with stronger growth in ventricular septal rupture diagnoses (OR = 1.43, 95% CI 0.95-2.18; P = 0.090). No significant differences in treatment types and mortality were found between the 2 periods. In-hospital mortality was 50.9% and was higher for conservatively managed cases (90.9%) and lower for surgical patients (44.0%). Patients admitted during COVID-19 more frequently had late-presenting infarction (OR = 2.47, 95% CI 1.24-4.92; P = 0.010), more stable conditions (OR = 2.61, 95% CI 1.27-5.35; P = 0.009) and higher EuroSCORE II (OR = 1.04, 95% CI 1.01-1.06; P = 0.006).

conclusionsA non-significant increase in MCs incidence occurred during the first year of COVID-19, characterized by a significantly higher rate of late-presenting infarction, stable conditions and EuroSCORE-II if compared to pre-pandemic data, without affecting treatment and mortality.

Indexed as

Acute myocardial infarctionCardiac ruptureCOVID-19Papillary muscle ruptureVentricular septal rupture

Identifiers

PMID38109676
PMCPMC10749759
OpenAlexW4389958284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.