Evidence map›Paper›PMID 38109073›Full record

ArticleACS chemical neuroscience2024

On-Tissue Spatial Proteomics Integrating MALDI-MS Imaging with Shotgun Proteomics Reveals Soy Consumption-Induced Protein Changes in a Fragile X Syndrome Mouse Model.

Min Ma, Qinying Yu, Daniel G Delafield, Yusi Cui, Zihui Li, Miyang Li, Wenxin Wu, Xudong Shi, Pamela R Westmark, Alejandra Gutierrez and 6 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Min MaSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Qinying YuSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Daniel G DelafieldSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0003-2989-9833
Yusi CuiDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Zihui LiDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Miyang LiDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Wenxin WuDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Xudong ShiDivision of Otolaryngology, Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Pamela R WestmarkDepartment of Neurology, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Alejandra GutierrezDepartment of Neurology, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Gui MaMcArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Ang GaoMcArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Meng XuDepartment of Chemistry, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Wei XuMcArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.
Cara J WestmarkDepartment of Neurology, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Lingjun LiSchool of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin 53705, United States.ORCID 0000-0003-0056-3869
University of Wisconsin–Madison · US

Funding

Mass Spectrometric Studies of Neuropeptides in FeedingR01DK071801 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI LINGJUN LI · 2006 to 2026
$6.7M
Creating a region- specific biomolecular atlas of the brain of Alzheimer’s diseaseR01AG078794 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LINGJUN LI, Luigi Puglielli · 2022 to 2026
$3.7M
DiLeu-enabled multiplexed quantitation for biomarker discovery and validation in Alzheimer’s diseaseR01AG052324 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI LINGJUN LI · 2023 to 2026
$2.3M
Acquisition of a High-Field Dual Source FTICR-MS for Pharmaceutical ResearchS10RR029531 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2011 to 2011
$2.1M
Acquisition of a Dual-Source, High-Performance, Ion Mobility, Quadrupole Time-of-Flight Mass Spectrometry System for Biomedical Research at UW-MadisonS10OD028473 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2021 to 2021
$1.3M
In Situ Protein Characterization and Visualization in the Brains of Mouse Models for AutismR56MH110215 · NIMH · UNIVERSITY OF WISCONSIN-MADISON · PI IKONOMIDOU, HRISSANTHI, LI, LINGJUN · 2017 to 2018
$752k
Acquisition of a High Resolution High Speed MALDI Mass Spectrometer for Biomedical Research at UW-MadisonS10OD025084 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI LI, LINGJUN · 2018 to 2018
$598k
NCRR NIH HHS S10 RR029531NIA NIH HHS R01 AG052324NIA NIH HHS R01 AG078794NIDDK NIH HHS R01 DK071801NIH HHS S10 OD025084NIH HHS S10 OD028473NIMH NIH HHS R56 MH110215
6 · The paper itself

Abstract

Fragile X syndrome (FXS), the leading cause of inherited intellectual disability and autism, is caused by the transcriptional silencing of the

Indexed as

Fragile X SyndromeSoybean ProteinsAnimalsDisease Models, AnimalFragile X Messenger Ribonucleoprotein 1MiceMice, KnockoutProteomicsSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1Soybean ProteinsFmr1FXSlabel-free quantificationMALDI-IMSspatial proteomicsWGCNA

Identifiers

PMID38109073
PMCPMC11127747
OpenAlexW4389890946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.