Evidence map›Paper›PMID 38108848›Full record

ReviewVirchows Archiv : an international journal of pathology2024

Molecular pathology of endocrine gland tumors: genetic alterations and clinicopathologic relevance.

Antonio De Leo, Martina Ruscelli, Thais Maloberti, Sara Coluccelli, Andrea Repaci, Dario de Biase, Giovanni Tallini

Erratum issuedOpen access · hybridAbstract readReview
In one paragraph

Review in Virchows Archiv : an international journal of pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Antonio De LeoDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138, Bologna, Italy.
Martina RuscelliDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138, Bologna, Italy.
Thais MalobertiDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138, Bologna, Italy.
Sara ColuccelliDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138, Bologna, Italy.
Andrea RepaciDivision of Endocrinology and Diabetes Prevention and Care, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
Dario de BiaseSolid Tumor Molecular Pathology Laboratory, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138, Bologna, Italy.
Giovanni TalliniDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138, Bologna, Italy. giovanni.tallini@unibo.it.
University of Bologna · ITAzienda USL di Bologna · IT

Funding

Ministero della Salute RC-2022-2773478
6 · The paper itself

Abstract

Tumors of the endocrine glands are common. Knowledge of their molecular pathology has greatly advanced in the recent past. This review covers the main molecular alterations of tumors of the anterior pituitary, thyroid and parathyroid glands, adrenal cortex, and adrenal medulla and paraganglia. All endocrine gland tumors enjoy a robust correlation between genotype and phenotype. High-throughput molecular analysis demonstrates that endocrine gland tumors can be grouped into molecular groups that are relevant from both pathologic and clinical point of views. In this review, genetic alterations have been discussed and tabulated with respect to their molecular pathogenetic role and clinicopathologic implications, addressing the use of molecular biomarkers for the purpose of diagnosis and prognosis and predicting response to molecular therapy. Hereditary conditions that play a key role in determining predisposition to many types of endocrine tumors are also discussed.

Indexed as

Adrenal Gland NeoplasmsEndocrine Gland NeoplasmsHumansMutationPathology, MolecularThyroid GlandAdrenal cortical tumorsEndocrine gland tumorsMolecular pathologyParaganglionic tumorsParathyroid tumorsPitNETThyroid tumors

Identifiers

PMID38108848
PMCPMC10948534
OpenAlexW4389885109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.