Evidence map›Paper›PMID 38108161›Full record

ArticleJoint diseases and related surgery2024

A secure blood-saving protocol for Jehovah's Witnesses in primary total hip replacement.

Mustafa Fatih Dasci, Ozkan Kose, Beatriz Fernandez Maza, Beren Gozacan, N Amir Sandiford, Thorsten Gehrke, Mustafa Citak

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Article in Joint diseases and related surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Mustafa Fatih Dasci
Ozkan Kose
Beatriz Fernandez Maza
Beren Gozacan
N Amir Sandiford
Thorsten Gehrke
Mustafa CitakENDO-Klinik Hamburg Department of Orthopaedic Surgery Holstenstr. 2, 22767 Hamburg, Germany. mcitak@gmx.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe study aimed to analyze the efficacy of the blood management protocol developed by our team for patients who are Jehovah's Witnesses (JW) presenting for primary total hip replacement (THR). PATIENTS AND

methodsThirty JW patients (6 males, 24 females; mean age: 70.1±9.8 years; range, 65 to 81 years) and 30 age- and sex-matched controls (6 males, 24 females; mean age: 68.7±9.1 years; range, 62 to 79 years) who underwent primary THR at our institution between January 2018 and June 2020 were retrospectively evaluated. While the surgical technique of THR was not different among the groups, blood loss management differed between the groups. Patients in the control group were given 1 g of intravenous tranexamic acid (TXA) 15 min before the surgical incision. In addition to the same TXA protocol, intraoperative cell salvage with a continuous autologous transfusion system was used for JW patients. The estimated blood loss (EBL) was determined using Meunier's formula. Hemoglobin (Hgb) decline, EBL on the first and third postoperative days, allogenic blood transfusion (ABT) requirement, and complications were analyzed between groups.

resultsThere were no significant differences between groups regarding demographic and clinical characteristics (p>0.05), ABT requirement (p>0.999), and Hgb decline in the first and third postoperative days (p=0.540 and p=0.836, respectively). Furthermore, both groups did not significantly differ between EBL in the first and third postoperative days (p=0.396 and p=0.616, respectively) and the length of hospital stay (p=0.547). Similar complication rates were noted for both groups. Hemoglobin level assessments revealed that values on the first and third postoperative days were significantly lower than the baseline Hgb value in both cohorts (p<0.001).

conclusionA combination of intravenous administration of 1 g of TXA, meticulous hemostasis, and intraoperative use of cell saver constitutes a reasonable strategy for achieving the goal of transfusion-free primary THR with predictable levels of blood loss that are similar to non-JW patients.

Indexed as

Arthroplasty, Replacement, HipJehovah's WitnessesOperative Blood SalvageTranexamic AcidAgedBlood Loss, SurgicalFemaleHemoglobinsHumansMaleMiddle AgedRetrospective StudiesHemoglobinsTranexamic Acid

Identifiers

PMID38108161
PMCPMC10746909

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.