Evidence map›Paper›PMID 38108020›Full record

ArticleTrends in chemistry2023

When all C-C breaks LO-Ose.

Jeremy H Dworkin, Brady W Dehnert, Ohyun Kwon

Open access · hybridAbstract read
In one paragraph

Article in Trends in chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Iron-Catalyzed Dealkenylative Borylation of Alkenes via Ozonolysis.Journal of the American Chemical Society · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Synthesis through C(spAccounts of chemical research · 2025
    Article
  6. Hydrodealkenylative C(spJournal of the American Chemical Society · 2025
    Article
  7. Deacylative Homolysis of Ketone C(spJournal of the American Chemical Society · 2025
    Article
  8. Article
  9. Advances in radical peroxidation with hydroperoxides.Beilstein journal of organic chemistry · 2024
    Review
  10. Hydrodealkenylative Cleavage of C(spOrganic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals · 2024
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jeremy H DworkinDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1569, USA.
Brady W DehnertDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1569, USA.
Ohyun KwonDepartment of Chemistry and Biochemistry, University of California, Los Angeles, CA 90095-1569, USA.ORCID 0000-0002-5405-3971
University of California, Los Angeles · US

Funding

Phosphine-Catalyzed Annulations and Their ApplicationsR01GM071779 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI OHYUN KWON · 2006 to 2026
$5.7M
Deconstructive Molecular Editing Technology Involving C-C Bond ScissionR01GM141327 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI KWON, OHYUN · 2021 to 2024
$1.4M
NIGMS NIH HHS R01 GM071779NIGMS NIH HHS R01 GM141327
6 · The paper itself

Abstract

Organic peroxides are becoming popular intermediates for novel chemical transformations. The weak O-O bond is readily reduced by transition metals, including iron and copper, to initiate a radical cascade process that breaks C-C bonds. Great potential exists for the rapid generation of complexity, originating from the ability to couple the resulting free radicals with a wide range of partners. First, this review article discusses the history and synthesis of organic peroxides, providing the context necessary to understand this methodology. Then, it highlights 91 examples of recent applications of the radical functionalization of C-C bonds accessed through the transition metal-mediated reduction of organic peroxides. Finally, we provide some comments about safety when working with organic peroxides.

Identifiers

PMID38108020
PMCPMC10725311
OpenAlexW4320732578

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.