Evidence map›Paper›PMID 38107605›Full record

ArticleACG case reports journal2023

Development of Shingles on Tofacitinib Despite Completion of Recombinant Varicella-Zoster Virus Vaccine Series.

Braden Thomas, Joshua Moskow, Manuel Garza, Benjamin Warren, Bincy Abraham, Kerri Glassner

Open access · diamondAbstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Braden ThomasInternal Medicine Residency Program, Houston Methodist Hospital, Houston, TX.
Joshua MoskowTexas A&M College of Medicine, EnMed, Houston, TX.
Manuel GarzaInternal Medicine Residency Program, Houston Methodist Hospital, Houston, TX.
Benjamin WarrenDivision of Gastroenterology and Hepatology, Houston Methodist Hospital, Houston, TX.
Bincy AbrahamDivision of Gastroenterology and Hepatology, Houston Methodist Hospital, Houston, TX.
Kerri GlassnerDivision of Gastroenterology and Hepatology, Houston Methodist Hospital, Houston, TX.
Methodist Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shingles, also known as herpes zoster, is caused by the reactivation of the varicella-zoster virus (VZV). The risk of developing shingles increases with age, as well as in patients with weakened immune systems. Tofacitinib is a reversible Janus kinase inhibitor that suppresses the immune system and is used to treat autoimmune diseases, such as ulcerative colitis. Recombinant VZV vaccine is recommended for individuals taking tofacitinib and is highly effective at reducing the risk of shingles. This case report describes a patient with severe, refractory ulcerative colitis who developed shingles while on tofacitinib, despite prior vaccination with the recombinant VZV vaccine.

Indexed as

herpes zostershinglestofacitinibulcerative colitisvaricella-zoster virus

Identifiers

PMID38107605
PMCPMC10723867
OpenAlexW4389784072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.