Evidence map›Paper›PMID 38107427›Full record

ArticleAdvanced functional materials2023

Hybrid Shear-thinning Hydrogel Integrating Hyaluronic Acid with ROS-Responsive Nanoparticles.

Mariah G Bezold, Andrew R Hanna, Bryan R Dollinger, Prarthana Patil, Fang Yu, Craig L Duvall, Mukesh K Gupta

Open access · bronzeAbstract read
In one paragraph

Article in Advanced functional materials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Mariah G BezoldDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.
Andrew R HannaDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.
Bryan R DollingerDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.
Prarthana PatilDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.
Fang YuDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.
Craig L DuvallDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.
Mukesh K GuptaDepartment of Biomedical Engineering, Vanderbilt University, Nashville, TN 37235 USA.
Vanderbilt University · US

Funding

Substrate Mediated siRNA Delivery from Scaffolds to Promote Wound RepairR01EB019409 · NIBIB · VANDERBILT UNIVERSITY · PI Craig Lewis Duvall · 2014 to 2026
$4.0M
Integrated Training in Engineering and DiabetesT32DK101003 · NIDDK · VANDERBILT UNIVERSITY · PI Jamey D. Young · 2014 to 2026
$3.9M
Tissue Adhesive RNA Interference Nanoparticles to Block Progression of Posttraumatic and Spontaneous Osteoarthritis.R01AR078666 · NIAMS · VANDERBILT UNIVERSITY · PI Craig Lewis Duvall · 2022 to 2026
$2.6M
Thermo Scientific Glacios cryo-TEMS10OD030292 · OD · VANDERBILT UNIVERSITY · PI NAKAGAWA, TERUNAGA · 2021 to 2021
$2.0M
Hybrid Synthetic and Biologic Shear Thinning Hydrogels for Diabetic Wound HealingR01EB028690 · NIBIB · VANDERBILT UNIVERSITY · PI DUVALL, CRAIG LEWIS, GUPTA, MUKESH KUMAR · 2019 to 2023
$2.0M
NIAMS NIH HHS R01 AR078666NIBIB NIH HHS R01 EB019409NIBIB NIH HHS R01 EB028690NIDDK NIH HHS T32 DK101003NIH HHS S10 OD030292
6 · The paper itself

Abstract

Nanoparticle (NP) supra-assembly offers unique opportunities to tune macroscopic hydrogels' mechanical strength, material degradation, and drug delivery properties. Here, synthetic, reactive oxygen species (ROS)-responsive NPs are physically crosslinked with hyaluronic acid (HA) through guest-host chemistry to create shear-thinning NP/HA hydrogels. A library of triblock copolymers composed of poly(propylene sulfide)-

Indexed as

guest-host chemistryhyaluronic acidreactive oxygen species (ROS) responsive polymershear-thinning hydrogelstriblock copolymer nanoparticles

Identifiers

PMID38107427
PMCPMC10723243
OpenAlexW4367679543

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.