Evidence map›Paper›PMID 38107259›Full record

ArticleFrontiers in cardiovascular medicine2023

Cusp-overlap view reduces conduction disturbances and permanent pacemaker implantation after transcatheter aortic valve replacement even with balloon-expandable and mechanically-expandable heart valves.

Tilman Stephan, Marvin Krohn-Grimberghe, Annika von Lindeiner Genannt von Wildau, Christoph Buck, Michael Baumhardt, Johannes Mörike, Birgid Gonska, Wolfgang Rottbauer, Dominik Buckert

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Pacemaker Implantation Rates With the Self-Expandable Navitor Valve.Journal of the American Heart Association · 2026
    Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Tilman Stephan *Department of Cardiology, Angiology, Pneumology and Internal Intensive Care, University of Ulm, Ulm, Germany.
Marvin Krohn-Grimberghe *Department of Cardiology, Angiology, Pneumology and Internal Intensive Care, University of Ulm, Ulm, Germany.
Annika von Lindeiner Genannt von WildauDepartment of Cardiology, Angiology, Pneumology and Internal Intensive Care, University of Ulm, Ulm, Germany.
Christoph BuckDepartment of Cardiology, Angiology, Pneumology and Internal Intensive Care, University of Ulm, Ulm, Germany.
Michael BaumhardtDepartment of Cardiology, Angiology, Pneumology and Internal Intensive Care, University of Ulm, Ulm, Germany.
Johannes MörikeDepartment of Cardiology, Angiology, Pneumology and Internal Intensive Care, University of Ulm, Ulm, Germany.
Birgid GonskaDepartment of Cardiology, Angiology, Pneumology and Internal Intensive Care, University of Ulm, Ulm, Germany.
Wolfgang RottbauerDepartment of Cardiology, Angiology, Pneumology and Internal Intensive Care, University of Ulm, Ulm, Germany.
Dominik BuckertDepartment of Cardiology, Angiology, Pneumology and Internal Intensive Care, University of Ulm, Ulm, Germany.
Universität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Conduction disturbances demanding permanent pacemaker implantation (PPI) remain a common complication after transcatheter aortic valve replacement (TAVR). Optimization of the implantation depth (ID) by introducing the cusp-overlap projection (COP) technique led to a reduced rate of PPI when self-expanding valves were used. Objectives: The aim of the present study was to determine if using the novel COP view is applicable for all types of TAVR prosthesis and results in a higher ID and reduced incidence of new conduction disturbances and PPI. Methods: In this prospective case-control study 586 consecutive patients undergoing TAVR with either balloon-expandable Edwards SAPIEN S3 ( Results: Of 586 patients, 282 (48.1%) underwent TAVR using COP, whereas in 304 patients (51.9%) the TCC view was applied. Using COP a significantly higher ID was achieved in Edwards SAPIEN S3 TAVR procedures (ID mean difference -1.0 mm, 95%-CI -1.9 to -0.1 mm; Conclusion: The present study demonstrates the safety, efficacy and reproducibility of the cusp-overlap view even in balloon-expandable and mechanically-expandable TAVR procedures. Application of COP leads to significantly less LBBB in repositionable Boston LOTUS Edge valves and a numerically lower PPI rate in Edwards SAPIEN S3 valves post TAVR compared to the standard TCC projection. The results should encourage to apply the COP view more widely in clinical practice.

Indexed as

aortic stenosisconduction disturbancecusp-overlap projectionimplantation depthimplantation techniquepermanent pacemaker implantationTAVRtranscatheter aortic valve replacement

Identifiers

PMID38107259
PMCPMC10722163
OpenAlexW4389246037

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.