Evidence map›Paper›PMID 38107199›Full record

ArticleiScience2023

Victoria A Riley, Vijay Shankar, Jennie C Holmberg, Aidan M Sokolov, Victoria N Neckles, Kaitlyn Williams, Rachel Lyman, Trudy F C Mackay, David M Feliciano

Open access · goldAbstract read
In one paragraph

Article in iScience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Victoria A RileyDepartment of Biological Sciences, Clemson University, Clemson, SC, USA.
Vijay ShankarDepartment of Biochemistry and Genetics, Clemson University, Clemson, SC, USA.
Jennie C HolmbergDepartment of Biological Sciences, Clemson University, Clemson, SC, USA.
Aidan M SokolovDepartment of Biological Sciences, Clemson University, Clemson, SC, USA.
Victoria N NecklesDepartment of Biological Sciences, Clemson University, Clemson, SC, USA.
Kaitlyn WilliamsClemson University Genomics and Bioinformatics Facility (CUGBF), Clemson University, Clemson, SC, USA.
Rachel LymanDepartment of Biochemistry and Genetics, Clemson University, Clemson, SC, USA.
Trudy F C MackayDepartment of Biochemistry and Genetics, Clemson University, Clemson, SC, USA.
David M FelicianoDepartment of Biological Sciences, Clemson University, Clemson, SC, USA.
Clemson University · USCenter for Human Genetics · USGreenwood Genetic Center · US

Funding

Project 3: Isolating food insecurity to understand childhood health outcomes and biological mechanisms of riskP20GM139767 · NIGMS · MIRIAM HOSPITAL · PI KayLoni L. Olson · 2021 to 2026
$14.6M
Regulation of Cryptosporidium DevelopmentP20GM146584 · NIGMS · CLEMSON UNIVERSITY · PI KERRY Scot SMITH · 2022 to 2026
$13.5M
Statistical Methods for Gene Regulatory Analysis From Single Cell Genomics DataP20GM139769 · NIGMS · CLEMSON UNIVERSITY · PI ANHOLT, ROBERT R. H, ARNO, GAVIN · 2021 to 2025
$10.8M
The role of acetate fermentation in Entamoeba histolytica growth and infectionP20GM109094 · NIGMS · CLEMSON UNIVERSITY · PI TEMESVARI, LESLY A · 2016 to 2020
$10.4M
NIGMS NIH HHS P20 GM109094NIGMS NIH HHS P20 GM139767NIGMS NIH HHS P20 GM139769NIGMS NIH HHS P20 GM146584
6 · The paper itself

Abstract

Neural stem cells (NSCs) of the ventricular-subventricular zone (V-SVZ) generate numerous cell types. The uncoupling of mRNA transcript availability and translation occurs during the progression from stem to differentiated states. The mTORC1 kinase pathway acutely controls proteins that regulate mRNA translation. Inhibiting mTORC1 during differentiation is hypothesized to be critical for brain development since somatic mutations of mTORC1 regulators perturb brain architecture. Inactivating mutations of

Indexed as

Cell biologyMolecular biologyMolecular mechanism of gene regulationNeuroscienceStem cells researchTranscriptomics

Identifiers

PMID38107199
PMCPMC10724693
OpenAlexW4388666264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.