Evidence map›Paper›PMID 38107179›Full record

ArticleRSC medicinal chemistry2023

Naphthyl bearing 1,3,4-thiadiazoleacetamides targeting the parasitic folate pathway as anti-infectious agents:

Kavita Pal, Sahil Lala, Priyanka Agarwal, Tarosh S Patel, Jenny Legac, Md Ataur Rahman, Saiema Ahmedi, Nida Shahid, Sneha Singh, Kajal Kumari and 7 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 6 institutions in 4 countries.

Kavita PalDrug Design and Synthesis Laboratory, Department of Chemistry, Jamia Millia Islamia New Delhi 110025 India nhoda@jmi.ac.in +91 11 26985507 +91 9910200655.
Sahil LalaPharmacology Division, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of Witwatersrand South Africa.ORCID https://orcid.org/0000-0002-1618-9755
Priyanka AgarwalPharmacology Division, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of Witwatersrand South Africa.
Tarosh S PatelChemistry Department, V. P. & R. P. T. P Science College, Affiliated to Sardar Patel University Vallabh Vidyanagar 388 120 Gujarat India.ORCID https://orcid.org/0000-0003-0196-3717
Jenny LegacDepartment of Medicine, University of California San Francisco CA USA.
Md Ataur RahmanChemistry Program, New York University Abu Dhabi (NYUAD) Saadiyat Island Abu Dhabi United Arab Emirates.
Saiema AhmediMedical Mycology Lab, Department of Biosciences, Jamia Millia Islamia New Delhi 110025 India.
Nida ShahidDepartment of Chemistry, Jamia Millia Islamia New Delhi India.
Sneha SinghDepartment of Molecular Biology, ICMR-Rajendra Memorial Research Institute of Medical Sciences Bihar India.
Kajal KumariDepartment of Molecular Biology, ICMR-Rajendra Memorial Research Institute of Medical Sciences Bihar India.
Hari MadhavDrug Design and Synthesis Laboratory, Department of Chemistry, Jamia Millia Islamia New Delhi 110025 India nhoda@jmi.ac.in +91 11 26985507 +91 9910200655.ORCID https://orcid.org/0000-0003-4992-096X
Abhik SenDepartment of Molecular Biology, ICMR-Rajendra Memorial Research Institute of Medical Sciences Bihar India.
Nikhat ManzoorMedical Mycology Lab, Department of Biosciences, Jamia Millia Islamia New Delhi 110025 India.
Bharat C DixitChemistry Department, V. P. & R. P. T. P Science College, Affiliated to Sardar Patel University Vallabh Vidyanagar 388 120 Gujarat India.
Robyn Van ZylPharmacology Division, Department of Pharmacy and Pharmacology, School of Therapeutic Sciences, Faculty of Health Sciences, University of Witwatersrand South Africa.
Philip J RosenthalDepartment of Medicine, University of California San Francisco CA USA.
Nasimul HodaDrug Design and Synthesis Laboratory, Department of Chemistry, Jamia Millia Islamia New Delhi 110025 India nhoda@jmi.ac.in +91 11 26985507 +91 9910200655.ORCID https://orcid.org/0000-0001-9779-2056
Jamia Millia Islamia · INRajendra Memorial Research Institute of Medical Sciences · INUniversity of the Witwatersrand · ZASardar Patel University · INUniversity of California, San Francisco · USNew York University Abu Dhabi · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malaria is still a complex and lethal parasitic infectious disease, despite the availability of effective antimalarial drugs. Resistance of malaria parasites to current treatments necessitates new antimalarials targeting

Identifiers

PMID38107179
PMCPMC10718588
OpenAlexW4388876054

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.