Evidence map›Paper›PMID 38107170›Full record

ReviewRSC medicinal chemistry2023

Research status of indole-modified natural products.

Song-Fang Duan, Lei Song, Hong-Yan Guo, Hao Deng, Xing Huang, Qing-Kun Shen, Zhe-Shan Quan, Xiu-Mei Yin

Abstract readReview
In one paragraph

Review in RSC medicinal chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Synthetic strategies and therapeutic insights into FDA-approved indole-containing drugs.Journal of enzyme inhibition and medicinal chemistry · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Song-Fang DuanKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Interdisciplinary Program of Biological Functional Molecules, College of Integration Science, Yanbian University Yanji 133002 China zsquan@ybu.edu.cn yinxm@ybu.edu.cn +86 0433 243 6020 +86 0433 243 6019.
Lei SongYanbian University Hospital, Yanbian University Yanji 133002 People's Republic of China.
Hong-Yan GuoKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Interdisciplinary Program of Biological Functional Molecules, College of Integration Science, Yanbian University Yanji 133002 China zsquan@ybu.edu.cn yinxm@ybu.edu.cn +86 0433 243 6020 +86 0433 243 6019.
Hao DengKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Interdisciplinary Program of Biological Functional Molecules, College of Integration Science, Yanbian University Yanji 133002 China zsquan@ybu.edu.cn yinxm@ybu.edu.cn +86 0433 243 6020 +86 0433 243 6019.
Xing HuangKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Interdisciplinary Program of Biological Functional Molecules, College of Integration Science, Yanbian University Yanji 133002 China zsquan@ybu.edu.cn yinxm@ybu.edu.cn +86 0433 243 6020 +86 0433 243 6019.
Qing-Kun ShenKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Interdisciplinary Program of Biological Functional Molecules, College of Integration Science, Yanbian University Yanji 133002 China zsquan@ybu.edu.cn yinxm@ybu.edu.cn +86 0433 243 6020 +86 0433 243 6019.
Zhe-Shan QuanKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Interdisciplinary Program of Biological Functional Molecules, College of Integration Science, Yanbian University Yanji 133002 China zsquan@ybu.edu.cn yinxm@ybu.edu.cn +86 0433 243 6020 +86 0433 243 6019.ORCID https://orcid.org/0009-0005-2419-3171
Xiu-Mei YinKey Laboratory of Natural Medicines of the Changbai Mountain, Ministry of Education, College of Pharmacy, Interdisciplinary Program of Biological Functional Molecules, College of Integration Science, Yanbian University Yanji 133002 China zsquan@ybu.edu.cn yinxm@ybu.edu.cn +86 0433 243 6020 +86 0433 243 6019.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Indole is a heterocyclic compound formed by the fusion of a benzene ring and pyrrole ring, which has rich biological activity. Many indole-containing compounds have been sold on the market due to their excellent pharmacological activity. For example, vincristine and reserpine have been widely used in clinical practice. The diverse structures and biological activities of natural products provide abundant resources for the development of new drugs. Therefore, this review classifies natural products by structure, and summarizes the research progress of indole-containing natural product derivatives, their biological activities, structure-activity relationship and research mechanism which has been studied in the past 13 years, so as to provide a basis for the development of new drug development.

Identifiers

PMID38107170
PMCPMC10718587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.