Evidence map›Paper›PMID 38106919›Full record

ArticleInterface focus2023

Evaluating pro-arrhythmogenic effects of the T634S-hERG mutation: insights from a simulation study.

Wei Hu, Wenfeng Zhang, Kevin Zhang, Ehab Al-Moubarak, Yihong Zhang, Stephen C Harmer, Jules C Hancox, Henggui Zhang

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Interface focus, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Wei HuBiological Physics Group, Department of Physics and Astronomy, University of Manchester, Manchester M13 9PL, UK.
Wenfeng ZhangCollege of Computer and Information Science, Chongqing Normal University, Chongqing, People's Republic of China.
Kevin ZhangSouthmead Hospital, North Bristol Trust, Bristol, UK.
Ehab Al-MoubarakSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Yihong ZhangSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Stephen C HarmerSchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Biomedical Sciences Building, University Walk, Bristol BS8 1TD, UK.
Jules C HancoxBiological Physics Group, Department of Physics and Astronomy, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-2055-6482
Henggui ZhangBiological Physics Group, Department of Physics and Astronomy, University of Manchester, Manchester M13 9PL, UK.ORCID 0000-0002-0863-5807
University of Bristol · GBUniversity of Manchester · GBChongqing Normal University · CNNorth Bristol NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A mutation to serine of a conserved threonine (T634S) in the hERG K

Indexed as

cardiac modellinghERGhuman ventriclesKCNH2long QT syndromeventricular fibrillation

Identifiers

PMID38106919
PMCPMC10722218
OpenAlexW4389794948

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.