Evidence map›Paper›PMID 38106623›Full record

ArticleIEEE transactions on radiation and plasma medical sciences2023

Experimental Evaluation of a 3-D CZT Imaging Spectrometer for Potential Use in Compton-Enhanced PET Imaging.

Yifei Jin, Michael Streicher, Hao Yang, Steven Brown, Zhong He, Ling-Jian Meng

Abstract read
In one paragraph

Article in IEEE transactions on radiation and plasma medical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Individual and Simultaneous Imaging ofIEEE transactions on radiation and plasma medical sciences · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yifei JinDepartment of Nuclear, Plasma and Radiological Engineering, University of Illinois at Urbana-Champaign, Urbana, IL 61801 USA.ORCID 0000-0002-3183-8741
Michael StreicherH3D, Inc., Ann Arbor, MI 48108 USA.
Hao YangH3D, Inc., Ann Arbor, MI 48108 USA.
Steven BrownH3D, Inc., Ann Arbor, MI 48108 USA.
Zhong HeH3D, Inc., Ann Arbor, MI 48108 USA.
Ling-Jian MengDepartment of Nuclear, Plasma and Radiological Engineering, Department of Bioengineering, Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801 USA.ORCID https://orcid.org/0000-0001-7806-1055

Funding

SPECT Imaging of Peripheral Vascular DiseaseR01HL145786 · NHLBI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI LIU, CHI, MENG, LING-JIAN · 2019 to 2022
$3.9M
Hyperspectral Single Photon Imaging of Targeted Alpha-EmittersR01EB031023 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI DU, YONG, GHALY, MICHAEL · 2021 to 2024
$2.7M
Dissemination of Advanced SPECT-MR Technology to the Molecular Imaging CommunityR01EB022388 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI CHEN, CHIN-TU, MENG, LING-JIAN · 2016 to 2019
$2.6M
Broadband X-ray Fluorescence Emission TomographyR01EB026300 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI LA RIVIERE, PATRICK JEAN, LU, YI · 2018 to 2021
$2.4M
NHLBI NIH HHS R01 HL145786NIBIB NIH HHS R01 EB022388NIBIB NIH HHS R01 EB026300NIBIB NIH HHS R01 EB031023
6 · The paper itself

Abstract

We constructed a prototype positron emission tomography (PET) system and experimentally evaluated large-volume 3-D cadmium zinc telluride (CZT) detectors for potential use in Compton-enhanced PET imaging. The CZT spectrometer offers sub-0.5-mm spatial resolution, an ultrahigh energy resolution (~1% @ 511 keV), and the capability of detecting multiple gamma-ray interactions that simultaneously occurred. The system consists of four CZT detector panels with a detection area of around 4.4 cm × 4.4 cm. The distance between the front surfaces of the two opposite CZT detector panels is ~80 mm. This system allows us to detect coincident annihilation photons and Compton interactions inside the detectors and then, exploit Compton kinematics to predict the first Compton interaction site and reject chance coincidences. We have developed a numerical integration technique to model the near-field Compton response that incorporates Doppler broadening, detector's finite resolutions, and the distance between the first and second interactions. This method was used to effectively reject random and scattered coincidence events. In the preliminary imaging studies, we have used point sources, line sources, a custom-designed resolution phantom, and a commercial image quality (IQ) phantom to demonstrate an imaging resolution of approximately 0.75 mm in PET images, and Compton-based enhancement.

Indexed as

cadmium zinc telluride (CZT) detectorCompton scatteringpositron emission tomography (PET)

Identifiers

PMID38106623
PMCPMC10723109

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.