Evidence map›Paper›PMID 38106568›Full record

ArticleKidney international reports2023

Chronic Myelomonocytic Leukemia Patients With Lysozyme Nephropathy and Renal Infiltration Display Markers of Severe Disease.

Marie-Camille Lafargue, Mickaël Bobot, Helmut G Rennke, Marie Essig, Martin Carre, Lucile Mercadal, Jonathan Farhi, Hamza Sakhi, Thibault Comont, Léonard Golbin and 12 more

Abstract read
In one paragraph

Article in Kidney international reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Clonal monocytosis of renal significance.Kidney international · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Marie-Camille LafargueDepartment of Nephrology, Tenon's Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.
Mickaël BobotCentre de Néphrologie et Transplantation Rénale, AP-HM, Hôpital de la Conception, CHU de la Conception, 13005, Marseille, France.
Helmut G RennkeDepartment of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Marie EssigDepartment of Nephrology, Assistance Publique-Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne-Billancourt, Université Paris-Saclay, Paris, France.
Martin CarreService d'Hématologie, Centre Hospitalier Universitaire, Grenoble, France.
Lucile MercadalDepartment of Nephrology and Renal Transplantation, Assistance Publique-Hôpitaux de Paris, Hôpital de La Pitié Salpêtrière, Paris, France.
Jonathan FarhiMaladies du Sang, CHU d'Angers, 49000 Angers, France.
Hamza SakhiDepartment of Nephrology and renal transplantation, Necker's Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Cité, Paris, France.
Thibault ComontDepartment of Internal Medicine, Institut universitaire du cancer de Toulouse, Centre Hospitalier Universitaire de Toulouse, Université Toulouse III - Paul Sabatier, Toulouse, France.
Léonard GolbinService de Néphrologie, Dialyse et Transplantation Rénale, CHU Rennes, Hôpital Pontchaillou, Rennes, France.
Pierre IsnardDepartment of Pathology, Université Paris Cité, Necker Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
Jonathan ChemounyHématologie Clinique, Centre Hospitalier de Valenciennes, Valenciennes, France.
Nathalie CambierDepartment of Haematology, Centre Hospitalier Le Mans, France.
Kamel LaribiCentre Hospitalier Le Mans, Le Mans, France.
Umut SelametDivision of Renal Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Leonardo V RiellaCenter of Transplantation Sciences, Department of Medicine, Division of Nephrology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States.
Olivier FainHôpital Saint-Antoine, Service de Médecine Interne et de l'Inflammation-(DHU i2B), F-75012, Assistance Publique-Hôpitaux de Paris, Paris, France.
Lionel AdèsHématologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, Paris, France.
Pierre FenauxHématologie, Hôpital Saint-Louis, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, Paris, France.
Camille CohenINSERM U1151 « mechanisms and therapeutic strategies of chronic kidney diseases », Hôpital Necker, Université Paris Cité, Paris, France; Service de Néphrologie et Transplantation rénale, Assistance Publique-Hôpitaux de Paris, Hôpital Necker, Paris, France.
Arsène MekinianHôpital Saint-Antoine, Service de Médecine Interne et de l'Inflammation-(DHU i2B), F-75012, Assistance Publique-Hôpitaux de Paris, Paris, France.
MINHEMON, GFM and French VEXAS group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Chronic myelomonocytic leukemia (CMML) is a hematologic disorder that is an overlap syndrome between myelodysplastic syndromes and myeloproliferative neoplasms, and can be associated with autoimmune and inflammatory diseases. This study aimed to describe kidney involvement in patients with CMML, their treatments, and outcomes. Methods: We conducted a French and American multicenter retrospective study in 15 centers, identifying patients with CMML with acute kidney injury (AKI), chronic kidney disease (CKD), and urine abnormalities. Results: Sixteen patients (males, Conclusion: In this cohort of patients with CMML with a kidney injury, the 2 most frequent renal complications were lysozyme-induced nephropathy and renal infiltration by the CMML. Kidney involvement should be closely monitored in patients with CMML.

Indexed as

acute kidney injurychronic myelomonocytic leukemia

Identifiers

PMID38106568
PMCPMC10719588

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.