ArticleQuantitative imaging in medicine and surgery2023
Diffusion along the perivascular space as a potential biomarker for glioma grading and isocitrate dehydrogenase 1 mutation status prediction.
Article in Quantitative imaging in medicine and surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The trial behind it
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- The diagnostic and prediction performance of MR diffusion kurtosis imaging in the glioma molecular classification: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Glymphatic system dysfunction in central nervous system malignancies: A narrative review.Neurosurgical review · 2026Review
- Validation of automated DTI-ALPS and free water index as potential survival stratification markers in IDH-wildtype glioblastoma.Neuroradiology · 2026Article
- Vascular permeability mediates contralateral glymphatic dysfunction across glioma grades and IDH status.Neuroradiology · 2026Article
- Diffusion tensor image analysis along the perivascular space may serve as a potential biomarker for differentiating glioma recurrence from pseudoprogression: a preliminary study.Quantitative imaging in medicine and surgery · 2026Article
- Altered perivascular diffusivity in glioblastoma: integrating DTI-ALPS index with radio-pathomic and histopathologic correlates.Journal of neuro-oncology · 2026Article
- Diffusion tensor image analysis along the perivascular space (DTI-ALPS) in Parkinson's disease patients with subjective cognitive decline.Frontiers in aging neuroscience · 2026Article
- Deep gray matter atrophy mediates the associations between glymphatic dysfunction and clinical disability in relapsing-remitting multiple sclerosis: a neuroimaging subgroup study.Frontiers in immunology · 2026Article
- Contralateral neurofluid dynamics predict survival in IDH wild-type glioblastoma: A DTI-ALPS and free water imaging study.Neuro-oncology · 2026Article
- Glymphatic system dysfunction in pediatric growth hormone deficiency evidenced by multiple MRI metrics.Quantitative imaging in medicine and surgery · 2026Article
- Altered Perivascular Diffusivity in Glioblastoma:Integrating DTI-ALPS Index with Radio-Pathomicand Histopathologic Correlates.Research square · 2025Article
- The glymphatic system in neurodegenerative diseases and brain tumors: mechanistic insights, biomarker advances, and therapeutic opportunities.Acta neuropathologica communications · 2025Review
- Glymphatic system dysfunction associated with player position in collegiate American football players: A DTI-ALPS study.Neuroimage. Reports · 2025Article
- Added prognostic value of histogram features from preoperative multi-modal diffusion MRI in predicting Ki-67 proliferation for adult-type diffuse gliomas.Quantitative imaging in medicine and surgery · 2025Article
- The glymphatic system in oncology: from the perspective of a radiation oncologist.Journal of radiation research · 2025Review
- Noninvasive assessment of glymphatic dysfunction and IDH mutation in glioma with DTI-ALPS and DTI metrics.Quantitative imaging in medicine and surgery · 2025Article
- Impaired glymphatic system in patent foramen ovale based on diffusion tensor imaging analysis along the perivascular space.Quantitative imaging in medicine and surgery · 2025Article
- Assessing glymphatic dysfunction using the diffusion tensor image analysis along the perivascular space (DTI-ALPS) index in gliomas and metastases.Polish journal of radiology · 2025Article
- Relationship between glymphatic system dysfunction and cognitive impairment in patients with mild-to-moderate chronic traumatic brain injury: an analysis of the analysis along the perivascular space (ALPS) index.Quantitative imaging in medicine and surgery · 2024Article
- Prediction of isocitrate dehydrogenase mutation status in WHO grade II glioma by diffusion kurtosis imaging.Polish journal of radiology · 2024Article
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The diffusion tensor image analysis along the perivascular space (DTI-ALPS) may have the potential to reflect glymphatic dysfunction in patients with glioma. The study aimed to determine the correlation of DTI-ALPS with glioma grade and isocitrate dehydrogenase 1 ( Methods: In this study, 81 patients with glioma and 31 healthy controls underwent magnetic resonance imaging (MRI) examination. The ALPS-index, fractional anisotropy (FA), mean diffusivity (MD), and mean kurtosis (MK) were calculated. Comparisons were made between the left and right hemispheres and between patients and controls. Results: In patients with glioma, the ALPS-index of the hemisphere ipsilateral to glioma was significantly lower than that of the hemisphere contralateral to glioma (1.417±0.177 Conclusions: The reduced ALPS-index may reflect tumor-induced glymphatic system impairment, and the ALPS-index may be able to complement conventional diffusion metrics in glioma grading and
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.