Evidence map›Paper›PMID 38106224›Full record

ArticlemedRxiv : the preprint server for health sciences2023

An amplicon-based Illumina and nanopore sequencing workflow for Chikungunya virus West Africa genotype.

Idrissa Dieng, Mignane Ndiaye, Mouhamed Kane, Diamilatou Balde, Maimouna Mbanne, Seynabou Mbaye Ba Souna Diop, Safietou Sankhe, Moussa Dia, Madeleine Dieng, Serge Freddy Moukaha Doukanda and 6 more

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Idrissa DiengVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Mignane NdiayeVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Mouhamed KaneVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Diamilatou BaldeVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Maimouna MbanneVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Seynabou Mbaye Ba Souna DiopVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Safietou SankheVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Moussa DiaVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Madeleine DiengVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Serge Freddy Moukaha DoukandaVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Ousmane FayeVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Amadou Alpha SallVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Ndongo DiaVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Gamou FallVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Oumar FayeVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Moussa Moise DiagneVirology Department, Institut Pasteur de Dakar, Dakar 220, Senegal.
Institut Pasteur de Dakar · SN

Funding

West African Center for Emerging Infectious DiseasesU01AI151801 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Robert W Cross, Scott C Weaver · 2020 to 2026
$10.1M
NIAID NIH HHS U01 AI151801
6 · The paper itself

Abstract

The Chikungunya virus, a global arbovirus, is currently causing a major outbreak in the Western African region, with the highest cases reported in Senegal and Burkina Faso. Recent molecular evolution analyses reveal that the strain responsible for the epidemic belongs to the West African genotype, with new mutations potentially impacting viral replication, antigenicity, and host adaptation. Real-time genomic monitoring is needed to track the virus's spread in new regions. A scalable West African genotype amplicon-based Whole Genome Sequencing for multiple Next Generation Sequencing platforms has been developed to support genomic investigations and identify epidemiological links during the virus's ongoing spread. This technology will help identify potential threats and support real-time genomic investigations in the ongoing spread of the virus.

Indexed as

amplicon-based sequencingChikungunyaOutbreakSenegalWest Africa genotype

Identifiers

PMID38106224
PMCPMC10723560
OpenAlexW4389515052

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.