In one paragraphArticle in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
16 authors.
Kia M BarclayDepartment of Neuroscience, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-3531-2229 Nora AbduljawadDepartment of Neuroscience, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-2220-1730 Zuolin ChengBradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA.ORCID 0000-0002-5197-5874 Min Woo KimHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.
Lu ZhouDepartment of Neuroscience, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.
Jin YangDepartment of Neuroscience, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.
Justin RustenhovenHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-9376-7424 Jose Mazzitelli PerezNeuroscience Graduate Program, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-3896-3553 Leon SmythHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-9861-3574 Wandy BeattyDepartment of Molecular Microbiology, Washington University School of Medicine in St. Louis, School of Medicine, St. Louis, MO 63110, USA.
JinChao HouHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.
Naresha SaligramaHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0003-2526-7150 Marco ColonnaHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0001-5222-4987 Guoqiang YuBradley Department of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USA.
Jonathan KipnisHope Center for Neurological Disorders, Washington University School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-3714-517X Qingyun LiDepartment of Neuroscience, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, USA.ORCID 0000-0002-3457-5967 Funding
Washington University Center for Cellular ImagingP30CA091842 · NCI · WASHINGTON UNIVERSITY · PI TIMOTHY J. EBERLEIN · 2001 to 2026
$128.0MNovel Genetically Encoded Indicators for Interrogating Neuron-Astrocyte Communication Across TimescalesU19NS123719 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI TIAN, LIN · 2021 to 2025
$10.7MDecoding Astrocyte Signaling in Neural Circuitry with Novel Computational Modeling and Analytical ToolsR01MH110504 · NIMH · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI YUE WANG · 2017 to 2026
$6.1MDissecting the origin, regulation and function of microglial subsets in Alzheimer's diseaseR01AG078512 · NIA · WASHINGTON UNIVERSITY · PI Qingyun Li · 2023 to 2026
$2.2MNCI NIH HHS P30 CA091842NIA NIH HHS R01 AG078512NIMH NIH HHS R01 MH110504NINDS NIH HHS U19 NS123719
6 · The paper itselfAbstract
Recent single-cell RNA sequencing studies have revealed distinct microglial states in development and disease. These include proliferative region-associated microglia (PAM) in developing white matter and disease-associated microglia (DAM) prevalent in various neurodegenerative conditions. PAM and DAM share a similar core gene signature and other functional properties. However, the extent of the dynamism and plasticity of these microglial states, as well as their functional significance, remains elusive, partly due to the lack of specific tools. Here, we report the generation of an inducible Cre driver line, Clec7a-CreER
Indexed as
Alzheimer’s DiseaseClec7a-CreERDepletionDevelopmentDisease-Associated MicrogliaHeterogeneityMicrogliaMultiple SclerosisPlasticityProliferative-Region Associated MicrogliaSingle-cell RNA Sequencing
Identifiers
PMID38106187
PMCPMC10723357
What OpenQuestion holds
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LicenceCC BY-NC-ND
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