Evidence map›Paper›PMID 38106186›Full record

ArticlebioRxiv : the preprint server for biology2024

Single-cell eQTL mapping in yeast reveals a tradeoff between growth and reproduction.

James Boocock, Noah Alexander, Leslie Alamo Tapia, Laura Walter-McNeill, Shivani Prashant Patel, Chetan Munugala, Joshua S Bloom, Leonid Kruglyak

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

James BoocockDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0003-0323-8818
Noah AlexanderDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
Leslie Alamo TapiaDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
Laura Walter-McNeillDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
Shivani Prashant PatelDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
Chetan MunugalaDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.
Joshua S BloomDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-7241-1648
Leonid KruglyakDepartment of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA.ORCID 0000-0002-8065-3057
Howard Hughes Medical Institute · US

Funding

Toward comprehensive genetic dissection of complex traits in yeastR01GM102308 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LEONID KRUGLYAK · 2012 to 2026
$3.3M
NIGMS NIH HHS R01 GM102308
6 · The paper itself

Abstract

Expression quantitative trait loci (eQTLs) provide a key bridge between noncoding DNA sequence variants and organismal traits. The effects of eQTLs can differ among tissues, cell types, and cellular states, but these differences are obscured by gene expression measurements in bulk populations. We developed a one-pot approach to map eQTLs in

Identifiers

PMID38106186
PMCPMC10723400
OpenAlexW4389498026

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.