Evidence map›Paper›PMID 38106030›Full record

ArticlebioRxiv : the preprint server for biology2023

Astrocyte coverage of excitatory synapses correlates to measures of synapse structure and function in primary visual cortex.

Connon I Thomas, Melissa A Ryan, Micaiah C McNabb, Naomi Kamasawa, Benjamin Scholl

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Connon I ThomasElectron Microscopy Core Facility, Max Planck Florida Institute for Neuroscience, 1 Max Planck Way, Jupiter, FL 33458, USA.ORCID 0000-0003-0995-9667
Melissa A RyanElectron Microscopy Core Facility, Max Planck Florida Institute for Neuroscience, 1 Max Planck Way, Jupiter, FL 33458, USA.
Micaiah C McNabbElectron Microscopy Core Facility, Max Planck Florida Institute for Neuroscience, 1 Max Planck Way, Jupiter, FL 33458, USA.ORCID 0000-0002-3307-1396
Naomi KamasawaElectron Microscopy Core Facility, Max Planck Florida Institute for Neuroscience, 1 Max Planck Way, Jupiter, FL 33458, USA.ORCID 0000-0002-8926-5309
Benjamin SchollDepartment of Physiology and Biophysics, University of Colorado Denver, 12800 East 19th Ave, Aurora, CO 80045, USA.ORCID 0000-0002-9578-7234
Max Planck Florida Institute for Neuroscience · USBaylor College of Medicine · USUniversity of Colorado Denver · US

Funding

PRINCIPLES OF PRESYNAPTIC NETWORKS FOR SINGLE LAYER 2/3 NEURONS IN FERRET VISUAL CORTEXR00EY031137 · NEI · UNIVERSITY OF PENNSYLVANIA · PI SCHOLL, BENJAMIN KYLE · 2021 to 2023
$967k
NEI NIH HHS R00 EY031137
6 · The paper itself

Abstract

Most excitatory synapses in the mammalian brain are contacted by astrocytes, forming the tripartite synapse. This interface is thought to be critical for glutamate turnover and structural or functional dynamics of synapses. While the degree of synaptic contact of astrocytes is known to vary across brain regions and animal species, the implications of this variability remain unknown. Furthermore, precisely how astrocyte coverage of synapses relates to

Identifiers

PMID38106030
PMCPMC10723302
OpenAlexW4389303710

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.