Evidence map›Paper›PMID 38105997›Full record

ArticlebioRxiv : the preprint server for biology2023

Regulatable assembly of synthetic microtubule architectures using engineered MAP-IDR condensates.

Chih-Chia Chang, Scott M Coyle

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chih-Chia ChangBiophysics Graduate Program, University of Wisconsin-Madison, Madison, WI, 53705, USA.
Scott M CoyleBiophysics Graduate Program, University of Wisconsin-Madison, Madison, WI, 53705, USA.ORCID 0000-0003-2451-8763
University of Wisconsin–Madison · US

Funding

Cellular FM-radios: seeing, probing, and perturbing single-cell protein activity dynamics in biological systems with frequency-barcoded spatiotemporal signaling circuitsDP2GM154329 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SCOTT M. COYLE · 2023 to 2026
$2.3M
NIGMS NIH HHS DP2 GM154329
6 · The paper itself

Abstract

Microtubules filaments are assembled into higher-order structures and machines critical for cellular processes using microtubule-associated proteins (MAPs). However, the design of synthetic MAPs that direct the formation of new structures in cells is challenging, as nanoscale biochemical activities must be organized across micron length-scales. Here we develop synthetic MAP-IDR condensates (synMAPs) that provide tunable and regulatable assembly of higher-order microtubule structures

Identifiers

PMID38105997
PMCPMC10723337
OpenAlexW4324378501

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.